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Ccng1 cyclin G1 [ Mus musculus (house mouse) ]

Gene ID: 12450, updated on 11-Apr-2024

Summary

Official Symbol
Ccng1provided by MGI
Official Full Name
cyclin G1provided by MGI
Primary source
MGI:MGI:102890
See related
Ensembl:ENSMUSG00000020326 AllianceGenome:MGI:102890
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in several processes, including mitotic G2 DNA damage checkpoint signaling; regulation of cyclin-dependent protein serine/threonine kinase activity; and syncytium formation. Predicted to act upstream of or within cell division. Predicted to be located in dendrite; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CCNG1 (cyclin G1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in heart adult (RPKM 67.7), bladder adult (RPKM 21.1) and 22 other tissues See more
Orthologs
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Genomic context

Location:
11 A5; 11 24.42 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (40639379..40646044, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (40748552..40755309, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_29231 Neighboring gene STARR-seq mESC enhancer starr_29232 Neighboring gene hyaluronan mediated motility receptor (RHAMM) Neighboring gene STARR-seq mESC enhancer starr_29234 Neighboring gene NudC domain containing 2 Neighboring gene STARR-seq mESC enhancer starr_29235 Neighboring gene predicted gene, 24446 Neighboring gene high mobility group box 1, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic G2 DNA damage checkpoint signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic cell cycle phase transition IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cyclin-dependent protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in syncytium formation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009831.3NP_033961.1  cyclin-G1

    See identical proteins and their annotated locations for NP_033961.1

    Status: VALIDATED

    Source sequence(s)
    AL646055
    Consensus CDS
    CCDS24550.1
    UniProtKB/Swiss-Prot
    O54779, P51945
    UniProtKB/TrEMBL
    Q3TKC9, Q3TV43, Q3TX40, Q3U5X0, Q5NC86
    Related
    ENSMUSP00000020576.8, ENSMUST00000020576.8
    Conserved Domains (1) summary
    pfam00134
    Location:16148
    Cyclin_N; Cyclin, N-terminal domain

RNA

  1. NR_184448.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL646055

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    40639379..40646044 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)