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Cat catalase [ Mus musculus (house mouse) ]

Gene ID: 12359, updated on 9-Sep-2018

Summary

Official Symbol
Catprovided by MGI
Official Full Name
catalaseprovided by MGI
Primary source
MGI:MGI:88271
See related
Ensembl:ENSMUSG00000027187 Vega:OTTMUSG00000014875
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cas1; Cs-1; Cas-1; 2210418N07
Expression
Biased expression in liver adult (RPKM 579.2), kidney adult (RPKM 214.7) and 12 other tissues See more
Orthologs

Genomic context

See Cat in Genome Data Viewer
Location:
2 E2; 2 54.43 cM
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (103453904..103485153, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (103294061..103325310, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene cDNA sequence BC016548 Neighboring gene E74-like factor 5 Neighboring gene RIKEN cDNA 8030431J09 gene Neighboring gene ankyrin repeat and BTB (POZ) domain containing 2 Neighboring gene N-acetyltransferase 10

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NADP binding ISO
Inferred from Sequence Orthology
more info
 
aminoacylase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
antioxidant activity ISO
Inferred from Sequence Orthology
more info
 
catalase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
catalase activity IDA
Inferred from Direct Assay
more info
PubMed 
catalase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
catalase activity ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
heme binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heme binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on peroxide as acceptor IDA
Inferred from Direct Assay
more info
PubMed 
peroxidase activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
UV protection ISO
Inferred from Sequence Orthology
more info
 
aerobic respiration IMP
Inferred from Mutant Phenotype
more info
PubMed 
cholesterol metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
hemoglobin metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
hydrogen peroxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrogen peroxide catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
hydrogen peroxide catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
hydrogen peroxide catabolic process ISO
Inferred from Sequence Orthology
more info
 
kidney development ISO
Inferred from Sequence Orthology
more info
 
negative regulation of NF-kappaB transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of NF-kappaB transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell division IEA
Inferred from Electronic Annotation
more info
 
positive regulation of phosphatidylinositol 3-kinase signaling IDA
Inferred from Direct Assay
more info
PubMed 
protein homotetramerization ISO
Inferred from Sequence Orthology
more info
 
protein tetramerization ISO
Inferred from Sequence Orthology
more info
 
response to hydrogen peroxide IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
response to oxidative stress IDA
Inferred from Direct Assay
more info
PubMed 
response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to oxidative stress ISO
Inferred from Sequence Orthology
more info
 
response to reactive oxygen species ISO
Inferred from Sequence Orthology
more info
 
triglyceride metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
ureteric bud development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
lysosome ISO
Inferred from Sequence Orthology
more info
 
mitochondrial intermembrane space ISO
Inferred from Sequence Orthology
more info
 
mitochondrion HDA PubMed 
peroxisomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxisome IDA
Inferred from Direct Assay
more info
PubMed 
peroxisome ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
catalase
Names
catalase 1
NP_033934.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009804.2NP_033934.2  catalase

    See identical proteins and their annotated locations for NP_033934.2

    Status: VALIDATED

    Source sequence(s)
    AK150893, AL773505, BY093963
    Consensus CDS
    CCDS16478.1
    UniProtKB/Swiss-Prot
    P24270
    Related
    ENSMUSP00000028610.3, OTTMUSP00000015802, ENSMUST00000028610.9, OTTMUST00000035344
    Conserved Domains (2) summary
    cd08156
    Location:68497
    catalase_clade_3; Clade 3 of the heme-binding enzyme catalase
    COG0753
    Location:17500
    KatE; Catalase [Inorganic ion transport and metabolism]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

    Range
    103453904..103485153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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