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Caml calcium modulating ligand [ Mus musculus (house mouse) ]

Gene ID: 12328, updated on 12-May-2024

Summary

Official Symbol
Camlprovided by MGI
Official Full Name
calcium modulating ligandprovided by MGI
Primary source
MGI:MGI:104728
See related
Ensembl:ENSMUSG00000021501 AllianceGenome:MGI:104728
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Camlg
Summary
Predicted to enable cell adhesion molecule binding activity and ubiquitin protein ligase binding activity. Involved in B cell homeostasis. Acts upstream of or within epidermal growth factor receptor signaling pathway and receptor recycling. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be part of GET complex. Is expressed in central nervous system; dorsal root ganglion; and retina. Orthologous to human CAMLG (calcium modulating ligand). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 23.2), CNS E18 (RPKM 22.1) and 28 other tissues See more
Orthologs
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Genomic context

See Caml in Genome Data Viewer
Location:
13 B1; 13 30.06 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (55770818..55780229)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (55623005..55632416)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene transmembrane p24 trafficking protein 9 Neighboring gene beta-1,4-galactosyltransferase 7 Neighboring gene DEAD box helicase 46 Neighboring gene RIKEN cDNA B230219D22 gene Neighboring gene STARR-seq mESC enhancer starr_34621

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cell adhesion molecule binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of GET complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of GET complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
guided entry of tail-anchored proteins factor CAMLG
Names
calcium signal-modulating cyclophilin ligand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007596.2NP_031622.2  guided entry of tail-anchored proteins factor CAMLG

    See identical proteins and their annotated locations for NP_031622.2

    Status: VALIDATED

    Source sequence(s)
    AK002895, BY632386, CF915604
    Consensus CDS
    CCDS26551.1
    UniProtKB/Swiss-Prot
    P49070, Q99JU5
    Related
    ENSMUSP00000021963.5, ENSMUST00000021963.5
    Conserved Domains (1) summary
    pfam14963
    Location:21290
    CAML; Calcium signal-modulating cyclophilin ligand

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    55770818..55780229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)