Camk2b calcium/calmodulin-dependent protein kinase II, beta [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Camk2bprovided by MGI
Official Full Name: calcium/calmodulin-dependent protein kinase II, betaprovided by MGI
Primary source: MGI:MGI:88257
See related: Ensembl:ENSMUSG00000057897 AllianceGenome:MGI:88257
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: CaMKII
Summary: Enables calmodulin-dependent protein kinase activity. Involved in regulation of neuron migration. Acts upstream of or within several processes, including activation of meiosis involved in egg activation; modulation of chemical synaptic transmission; and protein phosphorylation. Located in cytosol; postsynaptic density; and spindle midzone. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeletal musculature. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 54. Orthologous to human CAMK2B (calcium/calmodulin dependent protein kinase II beta). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in frontal lobe adult (RPKM 115.3), cortex adult (RPKM 97.8) and 5 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 A1; 11 3.89 cM

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (5919642..6016401, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (5969629..6066357, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CaMKII may regulate renal tubular epithelial cell apoptosis through YAP/NFAT2 in acute kidney injury mice.
Title: CaMKII may regulate renal tubular epithelial cell apoptosis through YAP/NFAT2 in acute kidney injury mice.
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
Title: Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
GluN1 antibody causes behavioral deficits in prepulse inhibition and memory through CaMKIIbeta signaling.
Title: GluN1 antibody causes behavioral deficits in prepulse inhibition and memory through CaMKIIβ signaling.
A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIbeta Signaling in Limb Girdle Muscular Dystrophy.
Title: A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy.
Synaptic memory requires CaMKII.
Title: Synaptic memory requires CaMKII.
Adeno-associated virus-mediated expression of an inactive CaMKIIbeta mutant enhances muscle mass and strength in mice.
Title: Adeno-associated virus-mediated expression of an inactive CaMKIIβ mutant enhances muscle mass and strength in mice.
CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles.
Title: CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles.
Loss of Camk2 in a Camk2a/Camk2b double-mutant mice is lethal.
Title: CAMK2-Dependent Signaling in Neurons Is Essential for Survival.
Study shows that autophosphorylation of F-actin binding domain of CaMKIIbeta is required for fear learning.
Title: Autophosphorylation of F-actin binding domain of CaMKIIβ is required for fear learning.
Region-specific overexpression of betaCaMKII in dentate gyrus (DG) impairs behavioral flexibility, and severely attenuates the NMDAR-dependent long-term depression (LTD) in DG medial perforant path, which is further confirmed by the diminished AMPAR internalization and dephosphorylation during LTD.
Title: Overexpression of βCaMKII impairs behavioral flexibility and NMDAR-dependent long-term depression in the dentate gyrus.

Submit: New GeneRIF Correction See all GeneRIFs (32)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (10) 1 citation
Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

BF405463 (e-PCR)
- UniSTS:247914

PMC145549P1 (e-PCR)
- UniSTS:271004

Camk2b (e-PCR), detects polymorphism
- UniSTS:141220

Homology

Homologs of the Camk2b gene: The Camk2b gene is conserved in human, cow, rat, chicken, zebrafish, and frog.
Orthologs from Annotation Pipeline: 427 organisms have orthologs with human gene Camk2b
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables calcium-dependent protein serine/threonine kinase activity	ISO Inferred from Sequence Orthology more info
enables calmodulin binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed
enables calmodulin-dependent protein kinase activity	IBA Inferred from Biological aspect of Ancestor more info	PubMed
enables calmodulin-dependent protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables calmodulin-dependent protein kinase activity	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables phospholipase binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase binding	ISO Inferred from Sequence Orthology more info
enables protein serine/threonine kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein serine/threonine kinase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables structural constituent of postsynaptic actin cytoskeleton	ISO Inferred from Sequence Orthology more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G1/S transition of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within activation of meiosis involved in egg activation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of apoptotic signaling pathway	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within calcium ion transport	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in cell projection morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within inhibitory G protein-coupled receptor phosphorylation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within long-term synaptic potentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within nervous system development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neuromuscular process controlling balance	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within peptidyl-serine phosphorylation	IDA Inferred from Direct Assay more info	PubMed
involved_in peptidyl-serine phosphorylation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of apoptotic signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of dendritic spine morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neuron projection development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of phospholipase A2 activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synapse maturation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein autophosphorylation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein autophosphorylation	ISO Inferred from Sequence Orthology more info
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of long-term neuronal synaptic plasticity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of neuron migration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of neuron migration	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein localization to plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in regulation of synapse maturation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of synaptic transmission, cholinergic	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to cadmium ion	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
part_of calcium- and calmodulin-dependent protein kinase complex	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in dendrite	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in perikaryon	ISO Inferred from Sequence Orthology more info
located_in postsynaptic density	IDA Inferred from Direct Assay more info	PubMed
is_active_in postsynaptic density	ISO Inferred from Sequence Orthology more info
located_in postsynaptic density	ISO Inferred from Sequence Orthology more info
located_in sarcoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in spindle midzone	IDA Inferred from Direct Assay more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: calcium/calmodulin-dependent protein kinase type II subunit beta

Names: CaMK II; caM kinase II subunit beta; caMK-II subunit beta

NP_001167524.1

EC 2.7.11.17

NP_001167525.1

EC 2.7.11.17

NP_031621.3

EC 2.7.11.17

XP_006514527.1

EC 2.7.11.17

XP_006514528.1

EC 2.7.11.17

XP_006514530.1

EC 2.7.11.17

XP_006514532.1

EC 2.7.11.17

XP_006514533.1

EC 2.7.11.17

XP_006514538.1

EC 2.7.11.17

XP_006514539.1

EC 2.7.11.17

XP_006514540.1

EC 2.7.11.17

XP_006514542.1

EC 2.7.11.17

XP_017169726.1

EC 2.7.11.17

XP_017169727.1

EC 2.7.11.17

XP_017169728.1

EC 2.7.11.17

XP_017169729.1

EC 2.7.11.17

XP_017169730.1

EC 2.7.11.17

XP_030101361.1

EC 2.7.11.17

XP_030101362.1

EC 2.7.11.17

XP_030101363.1

EC 2.7.11.17

XP_030101364.1

EC 2.7.11.17

XP_030101365.1

EC 2.7.11.17

XP_030101366.1

EC 2.7.11.17

XP_030101367.1

EC 2.7.11.17

XP_036012149.1

EC 2.7.11.17

XP_036012150.1

EC 2.7.11.17

XP_036012151.1

EC 2.7.11.17

XP_036012152.1

EC 2.7.11.17

XP_036012153.1

EC 2.7.11.17

XP_036012154.1

EC 2.7.11.17

XP_036012155.1

EC 2.7.11.17

XP_036012156.1

EC 2.7.11.17

XP_036012157.1

EC 2.7.11.17

XP_036012158.1

EC 2.7.11.17

XP_036012159.1

EC 2.7.11.17

XP_036012160.1

EC 2.7.11.17

XP_036012161.1

EC 2.7.11.17

XP_036012162.1

EC 2.7.11.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001174053.2 → NP_001167524.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1

See identical proteins and their annotated locations for NP_001167524.1

Status: VALIDATED

Source sequence(s)

AL611926, AL645469

Consensus CDS

CCDS48748.1

UniProtKB/TrEMBL

A0A8C6HSV6, Q68EG2, Q8BL41

Related

ENSMUSP00000087925.4, ENSMUST00000090443.10

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:413 → 540

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_001174054.2 → NP_001167525.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3

Status: VALIDATED

Source sequence(s)

AL611926, AL645469

Consensus CDS

CCDS48749.1

UniProtKB/TrEMBL

A0A8C6HRZ1, Q5SVI2, Q8BL41

Related

ENSMUSP00000105437.3, ENSMUST00000109812.9

Conserved Domains (2) summary

cd14086
Location:12 → 314

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:397 → 524

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_001417428.1 → NP_001404357.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 4

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417429.1 → NP_001404358.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 5

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417430.1 → NP_001404359.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 6

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417431.1 → NP_001404360.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 7

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417432.1 → NP_001404361.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 8

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417433.1 → NP_001404362.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 9

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417434.1 → NP_001404363.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 10

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417435.1 → NP_001404364.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 11

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_001417436.1 → NP_001404365.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 12

Status: VALIDATED

Source sequence(s)

AL611926, AL645469
NM_007595.6 → NP_031621.3 calcium/calmodulin-dependent protein kinase type II subunit beta isoform 2

See identical proteins and their annotated locations for NP_031621.3

Status: VALIDATED

Source sequence(s)

AL611926, AL645469

Consensus CDS

CCDS24411.1

UniProtKB/Swiss-Prot

P28652, Q5SVH9

UniProtKB/TrEMBL

A0A6P5QX21, A0A8C6HSH0, Q8BL41

Related

ENSMUSP00000105438.3, ENSMUST00000109813.9

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:410 → 537

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000077.7 Reference GRCm39 C57BL/6J

Range

5919642..6016401 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036156268.1 → XP_036012161.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X29

Conserved Domains (2) summary

pfam08332
Location:281 → 408

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_006514479.4 → XP_006514542.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X21

UniProtKB/TrEMBL

A0A6P7RIV5, Q5SVJ1

Related

ENSMUSP00000002817.6, ENSMUST00000002817.12

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:371 → 498

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006514476.3 → XP_006514539.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X14

UniProtKB/TrEMBL

A0A6P7REG9, Q5SVI0

Related

ENSMUSP00000099120.3, ENSMUST00000101586.3

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:386 → 513

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_030245507.2 → XP_030101367.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X34

Conserved Domains (2) summary

pfam08332
Location:210 → 337

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_030245506.2 → XP_030101366.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X33

Conserved Domains (2) summary

pfam08332
Location:225 → 352

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_036156269.1 → XP_036012162.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X31

Conserved Domains (2) summary

pfam08332
Location:249 → 376

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_030245502.2 → XP_030101362.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X22

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:370 → 497

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006514477.3 → XP_006514540.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X15

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:385 → 512

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017314239.3 → XP_017169728.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X9

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:411 → 538

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_030245505.2 → XP_030101365.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X32

Conserved Domains (2) summary

pfam08332
Location:234 → 361

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_030245504.2 → XP_030101364.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X30

Conserved Domains (2) summary

pfam08332
Location:250 → 377

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_006514475.3 → XP_006514538.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X13

UniProtKB/TrEMBL

A0A6P7RFS7

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:395 → 522

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036156258.1 → XP_036012151.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X11

Conserved Domains (2) summary

pfam08332
Location:405 → 532

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_036156261.1 → XP_036012154.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X18

Conserved Domains (2) summary

pfam08332
Location:381 → 508

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_030245501.2 → XP_030101361.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X10

Conserved Domains (2) summary

pfam08332
Location:406 → 533

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_036156267.1 → XP_036012160.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X28

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:370 → 471

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_006514470.5 → XP_006514533.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X8

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:494 → 621

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036156265.1 → XP_036012158.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X25

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:385 → 486

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_017314238.3 → XP_017169727.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X5

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:509 → 636

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036156266.1 → XP_036012159.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X27

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:371 → 472

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_006514469.4 → XP_006514532.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X7

Related

ENSMUSP00000091046.6, ENSMUST00000093355.12

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:495 → 622

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036156264.1 → XP_036012157.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X24

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:386 → 487

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_006514467.4 → XP_006514530.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X4

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:510 → 637

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036156260.1 → XP_036012153.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X17

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:410 → 511

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_006514465.4 → XP_006514528.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X2

See identical proteins and their annotated locations for XP_006514528.1

UniProtKB/TrEMBL

A0A8C6HR78, Q5SVJ0

Related

ENSMUSP00000019133.5, ENSMUST00000019133.11

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:534 → 661

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036156263.1 → XP_036012156.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X23

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:396 → 497

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_017314240.3 → XP_017169729.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X12

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:396 → 523

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017314237.3 → XP_017169726.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X3

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:520 → 647

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036156259.1 → XP_036012152.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X16

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:411 → 512

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_036156256.1 → XP_036012149.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X6

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

cl09109
Location:535 → 636

NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of ...
XM_006514464.4 → XP_006514527.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:535 → 662

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_030245503.2 → XP_030101363.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X26

Conserved Domains (2) summary

pfam08332
Location:349 → 476

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_036156262.1 → XP_036012155.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X20

Conserved Domains (2) summary

pfam08332
Location:373 → 500

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_017314241.3 → XP_017169730.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X19

Conserved Domains (2) summary

pfam08332
Location:374 → 501

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:38 → 142

PKc_like; Protein Kinases, catalytic domain
XM_036156257.1 → XP_036012150.1 calcium/calmodulin-dependent protein kinase type II subunit beta isoform X10

Conserved Domains (2) summary

pfam08332
Location:406 → 533

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain