U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fabp7 fatty acid binding protein 7, brain [ Mus musculus (house mouse) ]

Gene ID: 12140, updated on 5-Mar-2024

Summary

Official Symbol
Fabp7provided by MGI
Official Full Name
fatty acid binding protein 7, brainprovided by MGI
Primary source
MGI:MGI:101916
See related
Ensembl:ENSMUSG00000019874 AllianceGenome:MGI:101916
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MRG; Blbp; BFABP; B-FABP
Summary
Predicted to enable fatty acid binding activity. Acts upstream of or within cell proliferation in forebrain; neurogenesis; and prepulse inhibition. Located in several cellular components, including cell projection; cell-cell junction; and neuronal cell body. Is expressed in several structures, including central nervous system; cranial nerve; gut; peripheral nervous system; and retina. Orthologous to human FABP7 (fatty acid binding protein 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 518.0), CNS E14 (RPKM 302.8) and 4 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Fabp7 in Genome Data Viewer
Location:
10 B4; 10 29.25 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (57661019..57664546)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (57784923..57788450)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene protein kinase inhibitor beta, cAMP dependent, testis specific Neighboring gene predicted gene, 18253 Neighboring gene STARR-positive B cell enhancer mm9_chr10:57463328-57463629 Neighboring gene STARR-seq mESC enhancer starr_26751 Neighboring gene peptidylprolyl isomerase A pseudogene 10_506.1 Neighboring gene sphingomyelin phosphodiesterase, acid-like 3A Neighboring gene predicted gene, 53585 Neighboring gene STARR-seq mESC enhancer starr_26752 Neighboring gene double homeobox protein 4-like protein 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables fatty acid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables fatty acid binding TAS
Traceable Author Statement
more info
PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell proliferation in forebrain IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in fatty acid transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within neurogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within prepulse inhibition IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within startle response IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cell periphery IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell projection IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
PubMed 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
fatty acid-binding protein, brain
Names
brain lipid-binding protein
brain-type fatty acid-binding protein
fatty acid-binding protein 7
mammary-derived growth inhibitor-related

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021272.3NP_067247.1  fatty acid-binding protein, brain

    See identical proteins and their annotated locations for NP_067247.1

    Status: VALIDATED

    Source sequence(s)
    AK021271
    Consensus CDS
    CCDS23856.1
    UniProtKB/Swiss-Prot
    P51880, Q4FJK4
    UniProtKB/TrEMBL
    Q5NDA4
    Related
    ENSMUSP00000020024.6, ENSMUST00000020024.12
    Conserved Domains (1) summary
    pfam00061
    Location:8119
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    57661019..57664546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)