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Bhmt betaine-homocysteine methyltransferase [ Mus musculus (house mouse) ]

Gene ID: 12116, updated on 31-Jan-2019

Summary

Official Symbol
Bhmtprovided by MGI
Official Full Name
betaine-homocysteine methyltransferaseprovided by MGI
Primary source
MGI:MGI:1339972
See related
Ensembl:ENSMUSG00000074768
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Biased expression in liver adult (RPKM 336.5), liver E18 (RPKM 100.1) and 1 other tissue See more
Orthologs

Genomic context

See Bhmt in Genome Data Viewer
Location:
13; 13 C3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (93616891..93637758, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (94386846..94407713, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene cofilin 1, non-muscle pseudogene Neighboring gene predicted gene, 31977 Neighboring gene betaine-homocysteine methyltransferase 2 Neighboring gene dimethylglycine dehydrogenase precursor Neighboring gene expressed sequence AW495222

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC46866, MGC117976

Gene Ontology Provided by MGI

Function Evidence Code Pubs
betaine-homocysteine S-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
betaine-homocysteine S-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
betaine-homocysteine S-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
L-methionine salvage ISO
Inferred from Sequence Orthology
more info
 
amino-acid betaine metabolic process ISO
Inferred from Sequence Orthology
more info
 
methionine biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
methionine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
protein methylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
betaine--homocysteine S-methyltransferase 1
NP_057877.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016668.3NP_057877.1  betaine--homocysteine S-methyltransferase 1

    See identical proteins and their annotated locations for NP_057877.1

    Status: VALIDATED

    Source sequence(s)
    AI114914, AK077108, BG078929, BY773713, CB948151
    Consensus CDS
    CCDS36748.1
    UniProtKB/Swiss-Prot
    O35490
    Related
    ENSMUSP00000096912.4, ENSMUST00000099309.5
    Conserved Domains (1) summary
    pfam02574
    Location:23314
    S-methyl_trans; Homocysteine S-methyltransferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

    Range
    93616891..93637758 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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