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FAM186A family with sequence similarity 186 member A [ Homo sapiens (human) ]

Gene ID: 121006, updated on 23-Nov-2021

Summary

Official Symbol
FAM186Aprovided by HGNC
Official Full Name
family with sequence similarity 186 member Aprovided by HGNC
Primary source
HGNC:HGNC:26980
See related
Ensembl:ENSG00000185958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward testis (RPKM 4.7) See more
Orthologs
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Genomic context

See FAM186A in Genome Data Viewer
Location:
12q13.12
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (50326854..50396633, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (50721092..50790392, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene LIM domain and actin binding 1 Neighboring gene RNA, U6 small nuclear 1093, pseudogene Neighboring gene uncharacterized LOC107984505 Neighboring gene KIAA1586 pseudogene Neighboring gene ribosomal protein L26 pseudogene 33 Neighboring gene La ribonucleoprotein 4 Neighboring gene small nucleolar RNA, C/D box 133 Neighboring gene fragile site, folic acid type, rare, fra(12)(q13.1) Neighboring gene disco interacting protein 2 homolog B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145475.3NP_001138947.1  protein FAM186A

    See identical proteins and their annotated locations for NP_001138947.1

    Status: VALIDATED

    Source sequence(s)
    AC090058, AC140061, AI808315, AL833333, BG206781
    Consensus CDS
    CCDS44878.1
    UniProtKB/Swiss-Prot
    A6NE01
    Related
    ENSP00000329995.5, ENST00000327337.6
    Conserved Domains (2) summary
    PRK10715
    Location:12911491
    flk; flagella biosynthesis regulator; Provisional
    pfam03157
    Location:10451645
    Glutenin_hmw; High molecular weight glutenin subunit

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    50326854..50396633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006719231.3XP_006719294.1  protein FAM186A isoform X1

    UniProtKB/TrEMBL
    F5GYN0
    Related
    ENSP00000441337.1, ENST00000543111.5
    Conserved Domains (2) summary
    PRK10715
    Location:12911491
    flk; flagella biosynthesis regulator; Provisional
    pfam03157
    Location:10451645
    Glutenin_hmw; High molecular weight glutenin subunit
  2. XM_011537890.2XP_011536192.1  protein FAM186A isoform X2

    Conserved Domains (2) summary
    PRK10715
    Location:12911491
    flk; flagella biosynthesis regulator; Provisional
    pfam03157
    Location:10451645
    Glutenin_hmw; High molecular weight glutenin subunit
  3. XM_011537892.1XP_011536194.1  protein FAM186A isoform X3

    Conserved Domains (2) summary
    PRK10715
    Location:11481348
    flk; flagella biosynthesis regulator; Provisional
    pfam03157
    Location:9021502
    Glutenin_hmw; High molecular weight glutenin subunit
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