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Rplp0 ribosomal protein, large, P0 [ Mus musculus (house mouse) ]

Gene ID: 11837, updated on 8-Jan-2023

Summary

Official Symbol
Rplp0provided by MGI
Official Full Name
ribosomal protein, large, P0provided by MGI
Primary source
MGI:MGI:1927636
See related
Ensembl:ENSMUSG00000067274 AllianceGenome:MGI:1927636
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
36B4; Arbp; L10E
Summary
Predicted to enable large ribosomal subunit rRNA binding activity and peptide binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within cellular response to interleukin-4. Located in dendrite. Is expressed in several structures, including gonad; integumental system; liver; small intestine; and spleen. Orthologous to human RPLP0 (ribosomal protein lateral stalk subunit P0). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14.5 (RPKM 1138.0), liver E14 (RPKM 1116.3) and 28 other tissues See more
Orthologs
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Genomic context

See Rplp0 in Genome Data Viewer
Location:
5; 5 F
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115697526..115701788)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115559467..115563729)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S5 pseudogene Neighboring gene paxillin Neighboring gene predicted gene 13840 Neighboring gene GCN1 activator of EIF2AK4 Neighboring gene microRNA 7029 Neighboring gene RIKEN cDNA 1110006O24 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC107165, MGC107166

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables large ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptide binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to interleukin-4 IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in ribosomal large subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynapse ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
60S acidic ribosomal protein P0
Names
60S ribosomal protein L10E
acidic ribosomal phosphoprotein P0

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007475.5NP_031501.1  60S acidic ribosomal protein P0

    See identical proteins and their annotated locations for NP_031501.1

    Status: VALIDATED

    Source sequence(s)
    AC159539, AK029816, BF021407
    Consensus CDS
    CCDS19594.1
    UniProtKB/Swiss-Prot
    P14869, Q99L54
    UniProtKB/TrEMBL
    Q5M8R8
    Related
    ENSMUSP00000083705.6, ENSMUST00000086519.12
    Conserved Domains (1) summary
    PTZ00135
    Location:1275
    PTZ00135; 60S acidic ribosomal protein P0; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    115697526..115701788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)