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Alb albumin [ Mus musculus (house mouse) ]

Gene ID: 11657, updated on 24-Jan-2023

Summary

Official Symbol
Albprovided by MGI
Official Full Name
albuminprovided by MGI
Primary source
MGI:MGI:87991
See related
Ensembl:ENSMUSG00000029368 AllianceGenome:MGI:87991
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Alb1; Alb-1; BCL002
Summary
This gene encodes albumin, an abundant plasma protein essential for maintaining oncotic pressure that functions as a carrier protein for various molecules such as steriods and fatty acids in blood. This gene is primarily expressed in liver where the encoded protein undergoes proteolytic processing before secretion into the plasma. [provided by RefSeq, Oct 2015]
Expression
Biased expression in liver adult (RPKM 14891.4), liver E14.5 (RPKM 6823.5) and 1 other tissue See more
Orthologs
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Genomic context

See Alb in Genome Data Viewer
Location:
5 E1; 5 44.7 cM
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (90608729..90624461)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (90460870..90476602)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 17 Neighboring gene predicted gene 9958 Neighboring gene predicted gene, 35999 Neighboring gene albumin (Alb) 5' regulatory region Neighboring gene alpha fetoprotein (Afp) 5' regulatory region Neighboring gene alpha fetoprotein Neighboring gene afamin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables chaperone binding ISO
Inferred from Sequence Orthology
more info
 
enables enterobactin binding ISO
Inferred from Sequence Orthology
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables exogenous protein binding ISO
Inferred from Sequence Orthology
more info
 
enables fatty acid binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables modified amino acid binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to oxygen binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
 
enables pyridoxal phosphate binding ISO
Inferred from Sequence Orthology
more info
 
enables toxic substance binding ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular response to starvation ISO
Inferred from Sequence Orthology
more info
 
involved_in maintenance of mitochondrion location ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of circadian sleep/wake cycle, non-REM sleep ISO
Inferred from Sequence Orthology
more info
 
involved_in transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in basement membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in myelin sheath HDA PubMed 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
albumin
Names
albumin 1
serum albumin
NP_033784.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009654.4NP_033784.2  albumin preproprotein

    See identical proteins and their annotated locations for NP_033784.2

    Status: REVIEWED

    Source sequence(s)
    AK131891, BY131635, W41729
    Consensus CDS
    CCDS19412.1
    UniProtKB/Swiss-Prot
    P07724, Q8CG74
    UniProtKB/TrEMBL
    Q546G4
    Related
    ENSMUSP00000031314.9, ENSMUST00000031314.10
    Conserved Domains (2) summary
    smart00103
    Location:21204
    ALBUMIN; serum albumin
    pfam00273
    Location:223394
    Serum_albumin; Serum albumin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    90608729..90624461
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)