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FAM210B family with sequence similarity 210 member B [ Homo sapiens (human) ]

Gene ID: 116151, updated on 23-Nov-2023

Summary

Official Symbol
FAM210Bprovided by HGNC
Official Full Name
family with sequence similarity 210 member Bprovided by HGNC
Primary source
HGNC:HGNC:16102
See related
Ensembl:ENSG00000124098 MIM:618722; AllianceGenome:HGNC:16102
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
5A3; C20orf108; dJ1167H4.1
Summary
Involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Located in mitochondrial outer membrane. Is intrinsic component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary (RPKM 51.5), adrenal (RPKM 50.1) and 25 other tissues See more
Orthologs
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Genomic context

See FAM210B in Genome Data Viewer
Location:
20q13.2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (56358974..56368663)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (58136516..58146109)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (54934030..54943719)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 487 Neighboring gene NANOG hESC enhancer GRCh37_chr20:54792881-54793405 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13056 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:54834703-54835902 Neighboring gene melanocortin 3 receptor Neighboring gene Sharpr-MPRA regulatory region 10041 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13057 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:54937273-54937462 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:54938029-54938529 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr20:54961142-54962341 Neighboring gene aurora kinase A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18142 Neighboring gene cleavage stimulation factor subunit 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • DKFZp434A1114

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to estradiol stimulus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in erythrocyte maturation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein FAM210B, mitochondrial
Names
transmembrane protein C20orf108

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080821.3NP_543011.2  protein FAM210B, mitochondrial

    See identical proteins and their annotated locations for NP_543011.2

    Status: VALIDATED

    Source sequence(s)
    AK075565, AL133555, DB500825
    Consensus CDS
    CCDS13450.1
    UniProtKB/Swiss-Prot
    B2RBQ9, E1P5Y7, Q8WVN2, Q96KR6, Q9BYL6, Q9H418
    Related
    ENSP00000360437.3, ENST00000371384.4
    Conserved Domains (1) summary
    pfam06916
    Location:87174
    DUF1279; Protein of unknown function (DUF1279)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    56358974..56368663
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    58136516..58146109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)