U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fam210b family with sequence similarity 210, member B [ Mus musculus (house mouse) ]

Gene ID: 67017, updated on 9-Dec-2024

Summary

Official Symbol
Fam210bprovided by MGI
Official Full Name
family with sequence similarity 210, member Bprovided by MGI
Primary source
MGI:MGI:1914267
See related
Ensembl:ENSMUSG00000027495 AllianceGenome:MGI:1914267
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010011I20Rik
Summary
Predicted to be involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study systemic lupus erythematosus. Orthologous to human FAM210B (family with sequence similarity 210 member B). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in liver E14.5 (RPKM 40.7), liver E14 (RPKM 39.7) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Fam210b in Genome Data Viewer
Location:
2 H3; 2 94.83 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (172187444..172197669)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (172345570..172355749)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 40008 Neighboring gene predicted gene 14275 Neighboring gene STARR-seq mESC enhancer starr_06571 Neighboring gene predicted gene 14273 Neighboring gene aurora kinase A Neighboring gene cleavage stimulation factor, 3' pre-RNA, subunit 1 Neighboring gene STARR-seq mESC enhancer starr_06572 Neighboring gene STARR-positive B cell enhancer ABC_E823 Neighboring gene Cas scaffolding protein family member 4 Neighboring gene uncharacterized LOC118568483 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:172259262-172259485

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2)  1 citation
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein FAM210B, mitochondrial
Names
transmembrane protein C20orf108 homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025912.4NP_080188.3  protein FAM210B, mitochondrial

    See identical proteins and their annotated locations for NP_080188.3

    Status: VALIDATED

    Source sequence(s)
    AI504401, AK149497, AK160529
    Consensus CDS
    CCDS17128.1
    UniProtKB/Swiss-Prot
    Q3UFZ3, Q91WA2, Q9D8B6
    UniProtKB/TrEMBL
    Q3UFK7
    Related
    ENSMUSP00000028995.5, ENSMUST00000028995.5
    Conserved Domains (1) summary
    pfam06916
    Location:85172
    DUF1279; Protein of unknown function (DUF1279)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    172187444..172197669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500059.2XP_006500122.1  protein FAM210B, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_006500122.1

    UniProtKB/Swiss-Prot
    Q3UFZ3, Q91WA2, Q9D8B6
    UniProtKB/TrEMBL
    Q3UFK7
    Conserved Domains (1) summary
    pfam06916
    Location:85172
    DUF1279; Protein of unknown function (DUF1279)