Format

Send to:

Choose Destination

TSR3 TSR3 ribosome maturation factor [ Homo sapiens (human) ]

Gene ID: 115939, updated on 27-Jun-2020

Summary

Official Symbol
TSR3provided by HGNC
Official Full Name
TSR3 ribosome maturation factorprovided by HGNC
Primary source
HGNC:HGNC:14175
See related
Ensembl:ENSG00000007520 MIM:617058
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HsTsr3; C16orf42
Expression
Ubiquitous expression in fat (RPKM 23.3), kidney (RPKM 22.0) and 25 other tissues See more
Orthologs

Genomic context

See TSR3 in Genome Data Viewer
Location:
16p13.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (1349240..1351878, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (1399241..1401873, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 I Neighboring gene ribosomal protein S20 pseudogene 2 Neighboring gene BAI1 associated protein 3 Neighboring gene N-acetylglucosamine-1-phosphate transferase subunit gamma Neighboring gene unk like zinc finger Neighboring gene tight junction protein 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC24381

Gene Ontology Provided by GOA

Function Evidence Code Pubs
transferase activity EXP
Inferred from Experiment
more info
PubMed 
transferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
enzyme-directed rRNA pseudouridine synthesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
rRNA modification TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
18S rRNA aminocarboxypropyltransferase
Names
20S S rRNA accumulation protein 3 homolog
TSR3, 20S rRNA accumulation, homolog
TSR3, acp transferase ribosome maturation factor
probable ribosome biogenesis protein C16orf42
ribosome biogenesis protein TSR3 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001410.3NP_001001410.1  18S rRNA aminocarboxypropyltransferase

    See identical proteins and their annotated locations for NP_001001410.1

    Status: VALIDATED

    Source sequence(s)
    AL031709, BC016699, BC017325
    Consensus CDS
    CCDS10435.1
    UniProtKB/Swiss-Prot
    Q9UJK0
    Related
    ENSP00000007390.2, ENST00000007390.3
    Conserved Domains (3) summary
    PRK02287
    Location:65223
    PRK02287; hypothetical protein; Provisional
    pfam04034
    Location:96220
    DUF367; Domain of unknown function (DUF367)
    pfam04068
    Location:6092
    RLI; Possible Fer4-like domain in RNase L inhibitor, RLI

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    1349240..1351878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center