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SMIM12 small integral membrane protein 12 [ Homo sapiens (human) ]

Gene ID: 113444, updated on 1-Jun-2020

Summary

Official Symbol
SMIM12provided by HGNC
Official Full Name
small integral membrane protein 12provided by HGNC
Primary source
HGNC:HGNC:25154
See related
Ensembl:ENSG00000163866
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1orf212
Expression
Ubiquitous expression in adrenal (RPKM 3.5), kidney (RPKM 3.1) and 25 other tissues See more
Orthologs

Genomic context

See SMIM12 in Genome Data Viewer
Location:
1p34.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (34850362..34859749, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (35315963..35325417, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378642 Neighboring gene gap junction protein beta 3 Neighboring gene gap junction protein alpha 4 Neighboring gene DLG associated protein 3 Neighboring gene uncharacterized LOC653160

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90372, MGC138436

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small integral membrane protein 12
Names
UPF0767 protein C1orf212
alternative protein C1orf212

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164824.1NP_001158296.1  small integral membrane protein 12

    See identical proteins and their annotated locations for NP_001158296.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI467795, AL122010, BG702416
    Consensus CDS
    CCDS53295.1
    UniProtKB/Swiss-Prot
    Q96EX1
    UniProtKB/TrEMBL
    L0R6D7
    Related
    ENSP00000428541.1, ENST00000417239.1
    Conserved Domains (1) summary
    pfam15990
    Location:187
    UPF0767; UPF0767 family
  2. NM_001164825.2NP_001158297.1  small integral membrane protein 12

    See identical proteins and their annotated locations for NP_001158297.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI467795, AL122010, BP234122
    Consensus CDS
    CCDS53295.1
    UniProtKB/Swiss-Prot
    Q96EX1
    UniProtKB/TrEMBL
    L0R6D7
    Related
    ENSP00000428984.1, ENST00000423898.1
    Conserved Domains (1) summary
    pfam15990
    Location:187
    UPF0767; UPF0767 family
  3. NM_001320261.2NP_001307190.1  small integral membrane protein 12

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI467795, AK074853, AL122010, BI759434, HY071448
    Consensus CDS
    CCDS53295.1
    UniProtKB/Swiss-Prot
    Q96EX1
    UniProtKB/TrEMBL
    L0R6D7
    Related
    ENSP00000430198.1, ENST00000456842.1
    Conserved Domains (1) summary
    pfam15990
    Location:187
    UPF0767; UPF0767 family
  4. NM_138428.6NP_612437.3  small integral membrane protein 12

    See identical proteins and their annotated locations for NP_612437.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI467795, AL122010, BC064320
    Consensus CDS
    CCDS53295.1
    UniProtKB/Swiss-Prot
    Q96EX1
    UniProtKB/TrEMBL
    L0R6D7
    Related
    ENSP00000428585.1, ENST00000521580.3
    Conserved Domains (1) summary
    pfam15990
    Location:187
    UPF0767; UPF0767 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    34850362..34859749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005270403.4XP_005270460.1  small integral membrane protein 12 isoform X2

    See identical proteins and their annotated locations for XP_005270460.1

    UniProtKB/Swiss-Prot
    Q96EX1
    UniProtKB/TrEMBL
    L0R6D7
    Related
    ENSP00000430285.1, ENST00000446026.1
    Conserved Domains (1) summary
    pfam15990
    Location:187
    UPF0767; UPF0767 family
  2. XM_011540554.3XP_011538856.2  small integral membrane protein 12 isoform X1

  3. XM_011540555.3XP_011538857.1  small integral membrane protein 12 isoform X2

    See identical proteins and their annotated locations for XP_011538857.1

    UniProtKB/Swiss-Prot
    Q96EX1
    UniProtKB/TrEMBL
    L0R6D7
    Conserved Domains (1) summary
    pfam15990
    Location:187
    UPF0767; UPF0767 family
  4. XM_011540553.2XP_011538855.1  small integral membrane protein 12 isoform X2

    See identical proteins and their annotated locations for XP_011538855.1

    UniProtKB/Swiss-Prot
    Q96EX1
    UniProtKB/TrEMBL
    L0R6D7
    Conserved Domains (1) summary
    pfam15990
    Location:187
    UPF0767; UPF0767 family
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