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PARK7 Parkinsonism associated deglycase [ Homo sapiens (human) ]

Gene ID: 11315, updated on 26-Jul-2021

Summary

Official Symbol
PARK7provided by HGNC
Official Full Name
Parkinsonism associated deglycaseprovided by HGNC
Primary source
HGNC:HGNC:16369
See related
Ensembl:ENSG00000116288 MIM:602533
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DJ1; DJ-1; GATD2; HEL-S-67p
Summary
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in adrenal (RPKM 125.5), thyroid (RPKM 111.2) and 25 other tissues See more
Orthologs
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Genomic context

See PARK7 in Genome Data Viewer
Location:
1p36.23
Exon count:
8
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (7961711..7985505)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (8021771..8045565)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene urotensin 2 Neighboring gene tRNA-undetermined (NNN) 4-1 Neighboring gene TNF receptor superfamily member 9 Neighboring gene ERBB receptor feedback inhibitor 1 Neighboring gene ribosomal protein L7a pseudogene 18

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
GeneReviews: Not available
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
GeneReviews: Not available
Multiple common variants for celiac disease influencing immune gene expression.
GeneReviews: Not available
Parkinson disease 7
MedGen: C1853445 OMIM: 606324 GeneReviews: Parkinson Disease Overview
Compare labs
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
GeneReviews: Not available

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat upregulates the expression of parkinson protein 7 (PARK7; DJ1) in Jurkat cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ27376, FLJ34360, FLJ92274

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables L-dopa decarboxylase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables androgen receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables cadherin binding HDA PubMed 
enables copper ion binding IDA
Inferred from Direct Assay
more info
PubMed 
NOT enables core promoter sequence-specific DNA binding IC
Inferred by Curator
more info
PubMed 
enables cupric ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cuprous ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cytokine binding IPI
Inferred from Physical Interaction
more info
PubMed 
NOT enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables glyoxalase (glycolic acid-forming) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mercury ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables oxidoreductase activity, acting on peroxide as acceptor IDA
Inferred from Direct Assay
more info
PubMed 
enables oxygen sensor activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein deglycase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NOT enables protein deglycase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein deglycase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein-containing complex binding IDA
Inferred from Direct Assay
more info
PubMed 
enables scaffold protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
NOT enables single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables small protein activating enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables superoxide dismutase copper chaperone activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription coactivator activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables transcription coactivator activity TAS
Traceable Author Statement
more info
PubMed 
enables transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables tyrosine 3-monooxygenase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ubiquitin-like protein conjugating enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin-specific protease binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA repair IDA
Inferred from Direct Assay
more info
PubMed 
involved_in Ras protein signal transduction TAS
Traceable Author Statement
more info
PubMed 
involved_in activation of protein kinase B activity IC
Inferred by Curator
more info
PubMed 
involved_in adult locomotory behavior IEA
Inferred from Electronic Annotation
more info
 
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular detoxification of aldehyde IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular detoxification of methylglyoxal IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to glyoxal IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to hydrogen peroxide IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to oxidative stress IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in detection of oxidative stress IEA
Inferred from Electronic Annotation
more info
 
involved_in detoxification of copper ion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in detoxification of mercury ion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in dopamine uptake involved in synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
involved_in glucose homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in glutathione deglycation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in glycolate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in glyoxal catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glyoxal metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in guanine deglycation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in guanine deglycation, glyoxal removal IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in guanine deglycation, glyoxal removal IDA
Inferred from Direct Assay
more info
PubMed 
involved_in guanine deglycation, methylglyoxal removal IDA
Inferred from Direct Assay
more info
PubMed 
involved_in histone modification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in hydrogen peroxide metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in insulin secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in lactate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in membrane depolarization IEA
Inferred from Electronic Annotation
more info
 
involved_in membrane hyperpolarization IEA
Inferred from Electronic Annotation
more info
 
involved_in methylglyoxal catabolic process to lactate IDA
Inferred from Direct Assay
more info
PubMed 
NOT involved_in methylglyoxal metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in methylglyoxal metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in mitochondrion organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of TRAIL-activated apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of cell death IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of death-inducing signaling complex assembly IC
Inferred by Curator
more info
PubMed 
involved_in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of hydrogen peroxide-induced cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of hydrogen peroxide-induced neuron death IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of neuron apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of neuron death IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of oxidative stress-induced cell death IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of protein K48-linked deubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of protein acetylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of protein binding IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of protein binding IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of protein binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of protein export from nucleus IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of protein kinase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of protein phosphorylation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of protein sumoylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of protein ubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of reactive oxygen species biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of ubiquitin-protein transferase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of ubiquitin-specific protease activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-arginine deglycation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-arginine deglycation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidyl-cysteine deglycation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-lysine deglycation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of DNA-binding transcription factor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of DNA-binding transcription factor activity TAS
Traceable Author Statement
more info
PubMed 
involved_in positive regulation of L-dopa biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of L-dopa decarboxylase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of NAD(P)H oxidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of acute inflammatory response to antigenic stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of androgen receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of autophagy of mitochondrion NAS
Non-traceable Author Statement
more info
PubMed 
involved_in positive regulation of dopamine biosynthetic process IC
Inferred by Curator
more info
PubMed 
involved_in positive regulation of dopamine biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of gene expression TAS
Traceable Author Statement
more info
PubMed 
involved_in positive regulation of interleukin-8 production IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of mitochondrial electron transport, NADH to ubiquinone IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of oxidative phosphorylation uncoupler activity IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of peptidyl-serine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of protein kinase B signaling IC
Inferred by Curator
more info
PubMed 
involved_in positive regulation of protein localization to nucleus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of protein localization to nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of protein-containing complex assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of pyrroline-5-carboxylate reductase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of reactive oxygen species biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of superoxide dismutase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription regulatory region DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of tyrosine 3-monooxygenase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein deglycation, glyoxal removal IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein deglycation, glyoxal removal IDA
Inferred from Direct Assay
more info
PubMed 
NOT involved_in protein deglycation, methylglyoxal removal IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein deglycation, methylglyoxal removal IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein deglycation, methylglyoxal removal IMP
Inferred from Mutant Phenotype
more info
PubMed 
NOT involved_in protein deglycosylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein deglycosylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein deglycosylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein stabilization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein stabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
NOT involved_in regulation of TRAIL production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of androgen receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of histone acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of histone ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of inflammatory response ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of mitochondrial membrane potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of neuron apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of supramolecular fiber organization TAS
Traceable Author Statement
more info
PubMed 
involved_in single fertilization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in PML body IDA
Inferred from Direct Assay
more info
PubMed 
located_in adherens junction HDA PubMed 
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cell body IEA
Inferred from Electronic Annotation
more info
 
located_in chromatin IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular exosome HDA PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Parkinson disease protein 7
Names
Parkinson disease (autosomal recessive, early onset) 7
epididymis secretory sperm binding protein Li 67p
maillard deglycase
oncogene DJ1
parkinson protein 7
protein DJ-1
protein deglycase DJ-1
protein/nucleic acid deglycase DJ-1
NP_001116849.1
NP_009193.2
XP_005263481.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_008271.1 RefSeqGene

    Range
    5058..28852
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001123377.2NP_001116849.1  Parkinson disease protein 7

    See identical proteins and their annotated locations for NP_001116849.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) represents the shorter transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK312000, AL034417, D61380
    Consensus CDS
    CCDS93.1
    UniProtKB/Swiss-Prot
    Q99497
    UniProtKB/TrEMBL
    V9HWC2
    Related
    ENSP00000418770.1, ENST00000493678.5
    Conserved Domains (1) summary
    TIGR01383
    Location:5184
    not_thiJ; DJ-1 family protein
  2. NM_007262.5NP_009193.2  Parkinson disease protein 7

    See identical proteins and their annotated locations for NP_009193.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK312000, AL034417, BC008188, BP248330, D61380
    Consensus CDS
    CCDS93.1
    UniProtKB/Swiss-Prot
    Q99497
    UniProtKB/TrEMBL
    V9HWC2
    Related
    ENSP00000340278.5, ENST00000338639.10
    Conserved Domains (1) summary
    TIGR01383
    Location:5184
    not_thiJ; DJ-1 family protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    7961711..7985505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005263424.3XP_005263481.1  Parkinson disease protein 7 isoform X1

    See identical proteins and their annotated locations for XP_005263481.1

    UniProtKB/Swiss-Prot
    Q99497
    UniProtKB/TrEMBL
    V9HWC2
    Related
    ENSP00000366711.1, ENST00000377491.5
    Conserved Domains (1) summary
    TIGR01383
    Location:5184
    not_thiJ; DJ-1 family protein
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