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Kif22 kinesin family member 22 [ Mus musculus (house mouse) ]

Gene ID: 110033, updated on 8-Jul-2021

Summary

Official Symbol
Kif22provided by MGI
Official Full Name
kinesin family member 22provided by MGI
Primary source
MGI:MGI:109233
See related
Ensembl:ENSMUSG00000030677
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ki; Kid; Kif2; C81217; Kif22a; AU021460
Expression
Biased expression in CNS E11.5 (RPKM 35.8), liver E14 (RPKM 33.5) and 13 other tissues See more
Orthologs
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Genomic context

See Kif22 in Genome Data Viewer
Location:
7 F3; 7 69.29 cM
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126626901..126641639, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127027729..127042467, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134171245..134185934, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene proline-rich transmembrane protein 2 Neighboring gene predicted gene, 53372 Neighboring gene MYC-associated zinc finger protein (purine-binding transcription factor) Neighboring gene zymogen granule protein 16 Neighboring gene predicted gene, 22747

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in metaphase plate congression ISO
Inferred from Sequence Orthology
more info
 
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic metaphase plate congression ISO
Inferred from Sequence Orthology
more info
 
involved_in sister chromatid cohesion ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromatin IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of kinesin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in spindle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
kinesin-like protein KIF22
Names
kinesin family member 22A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145588.1NP_663563.1  kinesin-like protein KIF22

    See identical proteins and their annotated locations for NP_663563.1

    Status: VALIDATED

    Source sequence(s)
    BC003427
    Consensus CDS
    CCDS21855.1
    UniProtKB/Swiss-Prot
    Q3V300
    Related
    ENSMUSP00000032915.7, ENSMUST00000032915.8
    Conserved Domains (3) summary
    smart00129
    Location:38370
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01376
    Location:38361
    KISc_KID_like; Kinesin motor domain, KIF22/Kid-like subgroup
    pfam12836
    Location:591641
    HHH_3; Helix-hairpin-helix motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    126626901..126641639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507201.2XP_006507264.1  kinesin-like protein KIF22 isoform X1

    Conserved Domains (2) summary
    cd01376
    Location:38361
    KISc_KID_like; Kinesin motor domain, KIF22/Kid-like subgroup
    cl39090
    Location:591641
    ComEA; DNA uptake protein ComE and related DNA-binding proteins [Replication, recombination and repair]
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