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JTB jumping translocation breakpoint [ Homo sapiens (human) ]

Gene ID: 10899, updated on 1-Jun-2020

Summary

Official Symbol
JTBprovided by HGNC
Official Full Name
jumping translocation breakpointprovided by HGNC
Primary source
HGNC:HGNC:6201
See related
Ensembl:ENSG00000143543 MIM:604671
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PAR; hJT; HJTB; HSPC222
Expression
Ubiquitous expression in colon (RPKM 43.4), stomach (RPKM 38.7) and 25 other tissues See more
Orthologs

Genomic context

See JTB in Genome Data Viewer
Location:
1q21.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (153974269..153977674, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153946745..153951096, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene CREB regulated transcription coactivator 2 Neighboring gene solute carrier family 39 member 1 Neighboring gene microRNA 6737 Neighboring gene cAMP responsive element binding protein 3 like 4 Neighboring gene RAB13, member RAS oncogene family Neighboring gene ribosomal protein S27

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein kinase binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
membrane TAS
Traceable Author Statement
more info
PubMed 
midbody IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
midbody IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with spindle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein JTB
Names
jumping translocation breakpoint protein
prostate androgen-regulated protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006694.4NP_006685.1  protein JTB precursor

    See identical proteins and their annotated locations for NP_006685.1

    Status: VALIDATED

    Source sequence(s)
    AL358472
    Consensus CDS
    CCDS1057.1
    UniProtKB/Swiss-Prot
    O76095
    Related
    ENSP00000271843.4, ENST00000271843.9
    Conserved Domains (1) summary
    pfam05439
    Location:37143
    JTB; Jumping translocation breakpoint protein (JTB)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    153974269..153977674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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