Zfta zinc finger translocation associated [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zftaprovided by MGI
Official Full Name: zinc finger translocation associatedprovided by MGI
Primary source: MGI:MGI:1919667
See related: Ensembl:ENSMUSG00000053080 AllianceGenome:MGI:1919667
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2700081O15Rik
Summary: Predicted to be involved in negative regulation of transcription, DNA-templated. Is expressed in forebrain. Orthologous to human ZFTA (zinc finger translocation associated). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in whole brain E14.5 (RPKM 43.0), CNS E14 (RPKM 41.9) and 26 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 19; 19 A

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (7394990..7403273)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (7417625..7425908)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation.
Title: C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation.

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2) 1 citation

General gene information

Go to the top of the page Help

Markers

RH136024 (e-PCR)
- UniSTS:210020

AI848741 (e-PCR)
- UniSTS:181187

AW558451 (e-PCR)
- UniSTS:181189

40.MMHAP45FRF10.seq (e-PCR)
- UniSTS:124368

Homology

Homologs of the Zfta gene: The Zfta gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, and rat.
Orthologs from Annotation Pipeline: 242 organisms have orthologs with human gene Zfta
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in negative regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: zinc finger translocation-associated protein; uncharacterized protein C11orf95 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001401803.1 → NP_001388732.1 zinc finger translocation-associated protein isoform 2

Status: VALIDATED

Source sequence(s)

AC129188
NM_175381.7 → NP_780590.3 zinc finger translocation-associated protein isoform 1

See identical proteins and their annotated locations for NP_780590.3

Status: VALIDATED

Source sequence(s)

AC129188

Consensus CDS

CCDS29524.2

UniProtKB/Swiss-Prot

Q4VA45

UniProtKB/TrEMBL

Q6PCY2

Related

ENSMUSP00000123773.2, ENSMUST00000159348.3

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000085.7 Reference GRCm39 C57BL/6J

Range

7394990..7403273

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011247115.3 → XP_011245417.1 uncharacterized protein C11orf95 homolog isoform X1

Conserved Domains (1) summary

pfam18658
Location:638 → 705

zf-C2H2_12; Zinc-finger C2H2-type
XM_011247116.3 → XP_011245418.1 uncharacterized protein C11orf95 homolog isoform X2

Conserved Domains (1) summary

pfam18658
Location:265 → 332

zf-C2H2_12; Zinc-finger C2H2-type