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Krt9 keratin 9 [ Mus musculus (house mouse) ]

Gene ID: 107656, updated on 8-Feb-2024

Summary

Official Symbol
Krt9provided by MGI
Official Full Name
keratin 9provided by MGI
Primary source
MGI:MGI:96696
See related
Ensembl:ENSMUSG00000051617 AllianceGenome:MGI:96696
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
K9; EPPK; Krt1-9
Summary
Predicted to enable structural molecule activity. Involved in spermatogenesis. Predicted to be located in keratin filament and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; gonad; hemolymphoid system gland; metanephros; and respiratory system. Human ortholog(s) of this gene implicated in epidermolytic palmoplantar keratoderma. Orthologous to human KRT9 (keratin 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 2.3), cortex adult (RPKM 1.4) and 2 other tissues See more
Orthologs
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Genomic context

See Krt9 in Genome Data Viewer
Location:
11 D; 11 63.43 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (100077607..100084072, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100186781..100193246, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene keratin 19 Neighboring gene predicted gene, 39022 Neighboring gene STARR-seq mESC enhancer starr_30714 Neighboring gene keratin 14 Neighboring gene type I keratin KA11P

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization ISO
Inferred from Sequence Orthology
more info
 
involved_in skin development ISO
Inferred from Sequence Orthology
more info
 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 
is_active_in keratin filament IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in keratin filament ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
keratin, type I cytoskeletal 9
Names
CK-9
cytokeratin-9
keratin complex 1, acidic, gene 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201255.2NP_957707.2  keratin, type I cytoskeletal 9

    See identical proteins and their annotated locations for NP_957707.2

    Status: VALIDATED

    Source sequence(s)
    AL590873
    Consensus CDS
    CCDS25412.1
    UniProtKB/Swiss-Prot
    A2A4G3, Q6RHW0
    Related
    ENSMUSP00000055255.3, ENSMUST00000059707.3
    Conserved Domains (1) summary
    pfam00038
    Location:130441
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    100077607..100084072 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)