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Vps37c vacuolar protein sorting 37C [ Mus musculus (house mouse) ]

Gene ID: 107305, updated on 23-Jun-2021

Summary

Official Symbol
Vps37cprovided by MGI
Official Full Name
vacuolar protein sorting 37Cprovided by MGI
Primary source
MGI:MGI:2147661
See related
Ensembl:ENSMUSG00000048832
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AU042646; 5730409F24Rik
Expression
Ubiquitous expression in colon adult (RPKM 20.1), adrenal adult (RPKM 16.6) and 28 other tissues See more
Orthologs
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Genomic context

See Vps37c in Genome Data Viewer
Location:
19; 19 A
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10666095..10691992)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10688735..10714628)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (10763305..10788909)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene pepsinogen 5, group I Neighboring gene RIKEN cDNA 2210404E10 gene Neighboring gene CD5 antigen Neighboring gene RIKEN cDNA A430093F15 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein targeting to vacuole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of ESCRT I complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ESCRT I complex ISO
Inferred from Sequence Orthology
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vacuolar protein sorting-associated protein 37C
Names
ESCRT-I complex subunit VPS37C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361958.1NP_001348887.1  vacuolar protein sorting-associated protein 37C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AK158833, AK159309, BX635445
    Consensus CDS
    CCDS29585.1
    Related
    ENSMUSP00000158500.2, ENSMUST00000235927.2
    Conserved Domains (2) summary
    PHA03247
    Location:184313
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:5149
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  2. NM_001361959.1NP_001348888.1  vacuolar protein sorting-associated protein 37C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK158833, BX635445
    Conserved Domains (2) summary
    PHA03247
    Location:76205
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:241
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  3. NM_001361960.1NP_001348889.1  vacuolar protein sorting-associated protein 37C isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK150606, AK158833, BX635445
    Consensus CDS
    CCDS89345.1
    Related
    ENSMUSP00000158200.2, ENSMUST00000235921.2
    Conserved Domains (1) summary
    pfam07200
    Location:5119
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  4. NM_001361961.1NP_001348890.1  vacuolar protein sorting-associated protein 37C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC132247
    Consensus CDS
    CCDS29585.1
    Conserved Domains (2) summary
    PHA03247
    Location:184313
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:5149
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  5. NM_001361962.1NP_001348891.1  vacuolar protein sorting-associated protein 37C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC132247
    Consensus CDS
    CCDS29585.1
    Conserved Domains (2) summary
    PHA03247
    Location:184313
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:5149
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  6. NM_001361963.1NP_001348892.1  vacuolar protein sorting-associated protein 37C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC132247
    Conserved Domains (2) summary
    PHA03247
    Location:76205
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:241
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  7. NM_001361964.1NP_001348893.1  vacuolar protein sorting-associated protein 37C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC132247, AK159309, BX635445, CO426419
    Consensus CDS
    CCDS29585.1
    Conserved Domains (2) summary
    PHA03247
    Location:184313
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:5149
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  8. NM_181403.3NP_852068.1  vacuolar protein sorting-associated protein 37C isoform 1

    See identical proteins and their annotated locations for NP_852068.1

    Status: VALIDATED

    Source sequence(s)
    AC132247
    Consensus CDS
    CCDS29585.1
    UniProtKB/Swiss-Prot
    Q8R105
    Related
    ENSMUSP00000085264.6, ENSMUST00000087951.7
    Conserved Domains (2) summary
    PHA03247
    Location:184313
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:5149
    Mod_r; Modifier of rudimentary (Mod(r)) protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    10666095..10691992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161381.1XP_036017274.1  vacuolar protein sorting-associated protein 37C isoform X2

    Conserved Domains (2) summary
    PHA03247
    Location:76205
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:241
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  2. XM_036161382.1XP_036017275.1  vacuolar protein sorting-associated protein 37C isoform X2

    Conserved Domains (2) summary
    PHA03247
    Location:76205
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:241
    Mod_r; Modifier of rudimentary (Mod(r)) protein
  3. XM_006526574.5XP_006526637.1  vacuolar protein sorting-associated protein 37C isoform X1

    See identical proteins and their annotated locations for XP_006526637.1

    UniProtKB/Swiss-Prot
    Q8R105
    Conserved Domains (2) summary
    PHA03247
    Location:184313
    PHA03247; large tegument protein UL36; Provisional
    pfam07200
    Location:5149
    Mod_r; Modifier of rudimentary (Mod(r)) protein
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