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HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105867828, updated on 13-Mar-2024

Summary

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Gene symbol
HMGCS1
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 1
See related
Ensembl:ENSMICG00000001372
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 12 NC_033671.1 (101792764..101814743)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012204229.1 (42239..64261)

Chromosome 12 - NC_033671.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105867830 Neighboring gene ribonuclease UK114 pseudogene Neighboring gene C-C motif chemokine ligand 28 Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene uncharacterized LOC105867835 Neighboring gene uncharacterized LOC105867834 Neighboring gene zinc finger protein 131

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033671.1 Reference Mmur_3.0 Primary Assembly

    Range
    101792764..101814743
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012758209.2 → XP_012613663.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    See identical proteins and their annotated locations for XP_012613663.1

    UniProtKB/TrEMBL
    A0A8C5UQ63, A0A8C6EK16
    Related
    ENSMICP00000001247.2, ENSMICT00000001371.3
    Conserved Domains (3) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:16 → 186
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:187 → 469
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_012758210.2 → XP_012613664.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    See identical proteins and their annotated locations for XP_012613664.1

    UniProtKB/TrEMBL
    A0A8C5UQ63, A0A8C6EK16
    Conserved Domains (3) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:16 → 186
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:187 → 469
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal
Nucleotide Protein
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