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Csdc2 cold shock domain containing C2, RNA binding [ Mus musculus (house mouse) ]

Gene ID: 105859, updated on 11-Apr-2024


Official Symbol
Csdc2provided by MGI
Official Full Name
cold shock domain containing C2, RNA bindingprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000042109 AllianceGenome:MGI:2146027
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in regulation of mRNA stability. Predicted to act upstream of or within mRNA processing. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in brain; ganglia; and neural retina. Orthologous to human CSDC2 (cold shock domain containing C2). [provided by Alliance of Genome Resources, Apr 2022]
Broad expression in cerebellum adult (RPKM 66.3), frontal lobe adult (RPKM 63.2) and 15 other tissues See more
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Genomic context

15 E1; 15 38.28 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (81820960..81835142)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (81936759..81950941)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene PHD finger protein 5A Neighboring gene aconitase 2, mitochondrial Neighboring gene STARR-seq mESC enhancer starr_39272 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide H Neighboring gene STARR-positive B cell enhancer ABC_E2447 Neighboring gene STARR-seq mESC enhancer starr_39275 Neighboring gene phosphomannomutase 1 Neighboring gene STARR-seq mESC enhancer starr_39276 Neighboring gene cytochrome P450, family 2, subfamily d, polypeptide 67, pseudogene

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding ISO
Inferred from Sequence Orthology
more info
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
involved_in regulation of mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
located_in nucleus IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
cold shock domain-containing protein C2
RNA-binding protein PIPPin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145473.3NP_663448.2  cold shock domain-containing protein C2

    See identical proteins and their annotated locations for NP_663448.2

    Status: VALIDATED

    Source sequence(s)
    AC102103, AK028916, AK132493, BB871178, CO041050
    Consensus CDS
    Q3V1F0, Q91YQ3
    ENSMUSP00000044441.8, ENSMUST00000038757.8
    Conserved Domains (1) summary
    CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000081.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)