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MASP2 MBL associated serine protease 2 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105580873, updated on 13-Mar-2024

Summary

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Gene symbol
MASP2
Gene description
MBL associated serine protease 2
See related
Ensembl:ENSCATG00000039032
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012006482.1 (1753263..1774405)

NW_012006482.1Genomic Context describing neighboring genes Neighboring gene exosome component 10 Neighboring gene spermidine synthase Neighboring gene TAR DNA binding protein Neighboring gene uncharacterized LOC105580875 Neighboring gene cofilin-1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012006482.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation, lectin pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012006482.1 Reference Caty_1.0

    Range
    1753263..1774405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012049378.1 → XP_011904768.1  mannan-binding lectin serine protease 2

    UniProtKB/TrEMBL
    A0A2K5N2X8
    Related
    ENSCATP00000031852.1, ENSCATT00000056118.1
    Conserved Domains (7) summary
    smart00020
    Location:444 → 679
    Tryp_SPc; Trypsin-like serine protease
    smart00032
    Location:300 → 361
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    smart00042
    Location:28 → 134
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    smart00179
    Location:138 → 176
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:184 → 295
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:445 → 682
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:366 → 430
    Sushi; Sushi repeat (SCR repeat)
Nucleotide Protein
Heading Accession and Version

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