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CHRNA2 cholinergic receptor nicotinic alpha 2 subunit [ Colobus angolensis palliatus ]

Gene ID: 105513661, updated on 13-Mar-2024

Summary

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Gene symbol
CHRNA2
Gene description
cholinergic receptor nicotinic alpha 2 subunit
See related
Ensembl:ENSCANG00000030174
Gene type
protein coding
RefSeq status
MODEL
Organism
Colobus angolensis palliatus (sub-species: palliatus)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012115522.1 (3960238..3981494)

NW_012115522.1Genomic Context describing neighboring genes Neighboring gene clusterin Neighboring gene epoxide hydrolase 2 Neighboring gene protein tyrosine kinase 2 beta Neighboring gene tripartite motif containing 35 Neighboring gene stathmin 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012115522.1 Unplaced Scaffold Reference Cang.pa_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neuronal acetylcholine receptor subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cang.pa_1.0

Genomic

  1. NW_012115522.1 Reference Cang.pa_1.0

    Range
    3960238..3981494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011944589.1 → XP_011799979.1  neuronal acetylcholine receptor subunit alpha-2 isoform X1

    See identical proteins and their annotated locations for XP_011799979.1

    UniProtKB/TrEMBL
    A0A2K5IA54
    Related
    ENSCANP00000013520.1, ENSCANT00000036433.1
    Conserved Domains (3) summary
    TIGR00860
    Location:57 → 522
    LIC; Cation transporter family protein
    pfam02931
    Location:59 → 265
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:272 → 520
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  2. XM_011944592.1 → XP_011799982.1  neuronal acetylcholine receptor subunit alpha-2 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:57 → 507
    LIC; Cation transporter family protein
    pfam02931
    Location:59 → 250
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:257 → 505
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  3. XM_011944591.1 → XP_011799981.1  neuronal acetylcholine receptor subunit alpha-2 isoform X1

    See identical proteins and their annotated locations for XP_011799981.1

    UniProtKB/TrEMBL
    A0A2K5IA54
    Conserved Domains (3) summary
    TIGR00860
    Location:57 → 522
    LIC; Cation transporter family protein
    pfam02931
    Location:59 → 265
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:272 → 520
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
Nucleotide Protein
Heading Accession and Version

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