U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slain1 SLAIN motif family, member 1 [ Mus musculus (house mouse) ]

Gene ID: 105439, updated on 5-Mar-2024

Summary

Official Symbol
Slain1provided by MGI
Official Full Name
SLAIN motif family, member 1provided by MGI
Primary source
MGI:MGI:2145578
See related
Ensembl:ENSMUSG00000055717 AllianceGenome:MGI:2145578
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9630044O09Rik
Summary
Predicted to be involved in cytoplasmic microtubule organization; microtubule nucleation; and positive regulation of microtubule polymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to colocalize with microtubule plus-end. Is expressed in several structures, including brain; immune system; neural ectoderm; sensory organ; and somite. Orthologous to human SLAIN1 (SLAIN motif family member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 21.4), whole brain E14.5 (RPKM 19.0) and 18 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
14 E2.3; 14 52.75 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (103887664..103942343)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (103650228..103704907)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10840 Neighboring gene STARR-positive B cell enhancer ABC_E5464 Neighboring gene predicted gene, 34907 Neighboring gene STARR-seq mESC enhancer starr_37505 Neighboring gene sciellin Neighboring gene STARR-seq mESC enhancer starr_37506 Neighboring gene STARR-seq mESC enhancer starr_37507 Neighboring gene STARR-positive B cell enhancer ABC_E10841 Neighboring gene STARR-seq mESC enhancer starr_37509 Neighboring gene SLAIN motif family, member 1, opposite strand Neighboring gene STARR-seq mESC enhancer starr_37510 Neighboring gene predicted gene, 35197 Neighboring gene predicted gene, 35116 Neighboring gene STARR-seq mESC enhancer starr_37511 Neighboring gene endothelin receptor type B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2) 
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic microtubule organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in microtubule nucleation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of microtubule polymerization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with microtubule plus-end IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
SLAIN motif-containing protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361639.1NP_001348568.1  SLAIN motif-containing protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AK036190, BC079866, BX529670
    UniProtKB/TrEMBL
    F7D4S5
    Related
    ENSMUSP00000125128.2, ENSMUST00000160805.8
    Conserved Domains (1) summary
    pfam15301
    Location:185629
    SLAIN; SLAIN motif-containing family
  2. NM_198014.3NP_932131.2  SLAIN motif-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_932131.2

    Status: VALIDATED

    Source sequence(s)
    AK036190, BC079866, BX529670
    Consensus CDS
    CCDS27316.1
    UniProtKB/Swiss-Prot
    Q68FF7, Q8R3I6
    UniProtKB/TrEMBL
    F7D4S5
    Related
    ENSMUSP00000070592.8, ENSMUST00000069443.14
    Conserved Domains (1) summary
    pfam15301
    Location:185579
    SLAIN; SLAIN motif-containing family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    103887664..103942343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)