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SLAIN1 SLAIN motif family member 1 [ Homo sapiens (human) ]

Gene ID: 122060, updated on 1-Jun-2020

Summary

Official Symbol
SLAIN1provided by HGNC
Official Full Name
SLAIN motif family member 1provided by HGNC
Primary source
HGNC:HGNC:26387
See related
Ensembl:ENSG00000139737 MIM:610491
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C13orf32
Expression
Biased expression in brain (RPKM 39.3), testis (RPKM 10.8) and 7 other tissues See more
Orthologs

Genomic context

See SLAIN1 in Genome Data Viewer
Location:
13q22.3
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (77697674..77764242)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (78271989..78338377)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene putative UPF0607 protein ENSP00000383144 Neighboring gene serine palmitoyltransferase long chain base subunit 1 pseudogene 5 Neighboring gene microRNA 3665 Neighboring gene uncharacterized LOC112268121 Neighboring gene EDNRB antisense RNA 1 Neighboring gene VISTA enhancer hs1394 Neighboring gene EDNRB proximal promoter region Neighboring gene endothelin receptor type B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ30046, MGC131899

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SLAIN motif-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040153.3NP_001035243.2  SLAIN motif-containing protein 1 isoform A precursor

    See identical proteins and their annotated locations for NP_001035243.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform A.
    Source sequence(s)
    AK294201, BC045177, DA096260
    Consensus CDS
    CCDS31995.2
    UniProtKB/Swiss-Prot
    Q8ND83
    UniProtKB/TrEMBL
    Q7L0J2
    Related
    ENSP00000418707.1, ENST00000488699.5
    Conserved Domains (1) summary
    pfam15301
    Location:46426
    SLAIN; SLAIN motif-containing family
  2. NM_001242868.2NP_001229797.1  SLAIN motif-containing protein 1 isoform C

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate 5' exon, and thus differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (C) has a distinct and longer N-terminus, compared to isoform A.
    Source sequence(s)
    AL354831, BC045177, BG391962, BQ433296, DB500463
    Consensus CDS
    CCDS73588.1
    UniProtKB/TrEMBL
    A0A0A0MSS3, Q7L0J2
    Related
    ENSP00000400921.2, ENST00000418532.6
    Conserved Domains (1) summary
    pfam15301
    Location:209590
    SLAIN; SLAIN motif-containing family
  3. NM_001242869.1NP_001229798.1  SLAIN motif-containing protein 1 isoform D

    See identical proteins and their annotated locations for NP_001229798.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, uses a downstream in-frame start codon, and lacks an internal in-frame coding exon, compared to variant 1. The encoded isoform (D) is shorter at the N-terminus and lacks an internal segment, compared to isoform A. Both variants 4 and 5 encode isoform D.
    Source sequence(s)
    AK289600, DA096260, DA343547
    Consensus CDS
    CCDS55901.1
    UniProtKB/Swiss-Prot
    Q8ND83
    Related
    ENSP00000314443.5, ENST00000314070.9
    Conserved Domains (1) summary
    pfam15301
    Location:20191
    SLAIN; SLAIN motif-containing family
  4. NM_001242870.2NP_001229799.1  SLAIN motif-containing protein 1 isoform D

    See identical proteins and their annotated locations for NP_001229799.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, uses a downstream in-frame start codon, and lacks an internal in-frame coding exon, compared to variant 1. The encoded isoform (D) is shorter at the N-terminus and lacks an internal segment, compared to isoform A. Both variants 4 and 5 encode isoform D.
    Source sequence(s)
    AL834203, DA343547
    Consensus CDS
    CCDS55901.1
    UniProtKB/Swiss-Prot
    Q8ND83
    Conserved Domains (1) summary
    pfam15301
    Location:20191
    SLAIN; SLAIN motif-containing family
  5. NM_001242871.1NP_001229800.1  SLAIN motif-containing protein 1 isoform E

    See identical proteins and their annotated locations for NP_001229800.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, uses an alternate start codon, and includes an alternate splice site in its 5' coding region, compared to variant 1. The encoded isoform (E) has a distinct and shorter N-terminus, compared to isoform A.
    Source sequence(s)
    AK295423, BC045177, DA096260, DA343547
    Consensus CDS
    CCDS73589.1
    UniProtKB/TrEMBL
    B7Z326, Q7L0J2
    Related
    ENSP00000314546.8, ENST00000351546.7
    Conserved Domains (1) summary
    pfam15301
    Location:21304
    SLAIN; SLAIN motif-containing family
  6. NM_001366665.1NP_001353594.1  SLAIN motif-containing protein 1 isoform F precursor

    Status: VALIDATED

    Source sequence(s)
    AL354831
    Conserved Domains (1) summary
    pfam15301
    Location:46476
    SLAIN; SLAIN motif-containing family
  7. NM_001366666.1NP_001353595.1  SLAIN motif-containing protein 1 isoform B

    Status: VALIDATED

    Source sequence(s)
    AL354831
    Related
    ENSP00000351507.2, ENST00000358679.3
    Conserved Domains (1) summary
    pfam15301
    Location:1305
    SLAIN; SLAIN motif-containing family
  8. NM_144595.4NP_653196.1  SLAIN motif-containing protein 1 isoform B

    See identical proteins and their annotated locations for NP_653196.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (B) is shorter at the N-terminus, compared to isoform A.
    Source sequence(s)
    BC045177, DA343547
    Consensus CDS
    CCDS9460.1
    UniProtKB/Swiss-Prot
    Q8ND83
    UniProtKB/TrEMBL
    Q7L0J2
    Conserved Domains (1) summary
    pfam15301
    Location:1305
    SLAIN; SLAIN motif-containing family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

    Range
    77697674..77764242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002957451.1 RNA Sequence

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