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smarca4a SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a [ Esox lucius (northern pike) ]

Gene ID: 105013184, updated on 18-Jun-2024

Summary

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Gene symbol
smarca4a
Gene description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
See related
Ensembl:ENSELUG00000010247
Gene type
protein coding
RefSeq status
MODEL
Organism
Esox lucius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes; Esocidae; Esox
Also known as
smarca4
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 11
Exon count:
31
Annotation release Status Assembly Chr Location
104 current fEsoLuc1.pri (GCF_011004845.1) 11 NC_047579.1 (35966640..35983569, complement)
103 previous assembly Eluc_v4 (GCF_004634155.1) Linkage Group LG11 NC_025978.4 (19123403..19140333)

Chromosome 11 - NC_047579.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109616310 Neighboring gene low density lipoprotein receptor a Neighboring gene ITPRIP like 2 Neighboring gene multidrug resistance-associated protein 1 Neighboring gene uncharacterized LOC106024521

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
Names
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Esox lucius Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fEsoLuc1.pri Primary Assembly

Genomic

  1. NC_047579.1 Reference fEsoLuc1.pri Primary Assembly

    Range
    35966640..35983569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020051119.2 → XP_019906678.1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a isoform X5

    UniProtKB/TrEMBL
    A0A6Q2Y3D3
    Conserved Domains (8) summary
    cd05516
    Location:1447 → 1552
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:469 → 541
    HSA; domain in helicases and associated with SANT domains
    pfam07533
    Location:621 → 661
    BRK; BRK domain
    pfam08880
    Location:187 → 221
    QLQ
    pfam09606
    Location:26 → 326
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14619
    Location:1307 → 1374
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl25548
    Location:422 → 585
    DUF4670; Domain of unknown function (DUF4670)
    cl26465
    Location:755 → 1237
    SNF2_N; SNF2 family N-terminal domain

  2. XM_034295209.1 → XP_034151100.1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a isoform X2

    UniProtKB/TrEMBL
    A0A6Q2Y3D3
    Related
    ENSELUP00000056334.1, ENSELUT00000076864.2
    Conserved Domains (9) summary
    cd05516
    Location:1449 → 1554
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:470 → 542
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:757 → 1239
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:380 → 580
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:26 → 327
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07533
    Location:623 → 665
    BRK; BRK domain
    pfam08880
    Location:187 → 221
    QLQ
    pfam14619
    Location:1310 → 1376
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl28899
    Location:738 → 988
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

  3. XM_034295208.1 → XP_034151099.1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a isoform X1

    UniProtKB/TrEMBL
    A0A6Q2Y3D3
    Conserved Domains (9) summary
    cd05516
    Location:1449 → 1555
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:470 → 542
    HSA; domain in helicases and associated with SANT domains
    PLN03142
    Location:757 → 1239
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    COG1196
    Location:380 → 580
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam09606
    Location:26 → 327
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07533
    Location:623 → 665
    BRK; BRK domain
    pfam08880
    Location:187 → 221
    QLQ
    pfam14619
    Location:1310 → 1376
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl28899
    Location:738 → 988
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

  4. XM_020051120.2 → XP_019906679.1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a isoform X6

    UniProtKB/TrEMBL
    A0A6Q2Y3D3
    Related
    ENSELUP00000061588.2, ENSELUT00000076379.2
    Conserved Domains (8) summary
    cd05516
    Location:1447 → 1553
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:469 → 541
    HSA; domain in helicases and associated with SANT domains
    pfam07533
    Location:621 → 661
    BRK; BRK domain
    pfam08880
    Location:187 → 221
    QLQ
    pfam09606
    Location:26 → 326
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14619
    Location:1307 → 1374
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
    cl25548
    Location:422 → 585
    DUF4670; Domain of unknown function (DUF4670)
    cl26465
    Location:755 → 1237
    SNF2_N; SNF2 family N-terminal domain

  5. XM_013135835.3 → XP_012991289.1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a isoform X4

    UniProtKB/TrEMBL
    A0A6Q2Y3D3
    Related
    ENSELUP00000075916.2, ENSELUT00000069527.2
    Conserved Domains (9) summary
    cd05516
    Location:1449 → 1554
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:470 → 542
    HSA; domain in helicases and associated with SANT domains
    cd00046
    Location:781 → 920
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam08430
    Location:27 → 134
    Forkhead_N; Forkhead N-terminal region
    pfam00176
    Location:764 → 1059
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:1086 → 1201
    Helicase_C; Helicase conserved C-terminal domain
    pfam07533
    Location:623 → 663
    BRK; BRK domain
    pfam08880
    Location:187 → 221
    QLQ; QLQ
    pfam14619
    Location:1309 → 1376
    SnAC; Snf2-ATP coupling, chromatin remodelling complex

  6. XM_010874532.4 → XP_010872834.1  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a isoform X3

    See identical proteins and their annotated locations for XP_010872834.1

    UniProtKB/TrEMBL
    A0A3P8Y0M4, A0A6Q2Y3D3
    Related
    ENSELUP00000009645.1, ENSELUT00000003495.3
    Conserved Domains (9) summary
    cd05516
    Location:1449 → 1555
    Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...
    smart00573
    Location:470 → 542
    HSA; domain in helicases and associated with SANT domains
    cd00046
    Location:781 → 920
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam08430
    Location:27 → 134
    Forkhead_N; Forkhead N-terminal region
    pfam00176
    Location:764 → 1059
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:1086 → 1201
    Helicase_C; Helicase conserved C-terminal domain
    pfam07533
    Location:623 → 663
    BRK; BRK domain
    pfam08880
    Location:187 → 221
    QLQ; QLQ
    pfam14619
    Location:1309 → 1376
    SnAC; Snf2-ATP coupling, chromatin remodelling complex
Nucleotide Protein
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