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lig4 ligase IV, DNA, ATP-dependent [ Notothenia coriiceps (black rockcod) ]

Gene ID: 104961587, updated on 12-Mar-2024

Summary

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Gene symbol
lig4
Gene description
ligase IV, DNA, ATP-dependent
Gene type
protein coding
RefSeq status
MODEL
Organism
Notothenia coriiceps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Notothenioidei; Nototheniidae; Notothenia
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
100 current NC01 (GCF_000735185.1) Unplaced Scaffold NW_011334167.1 (223137..228145, complement)

NW_011334167.1Genomic Context describing neighboring genes Neighboring gene cholecystokinin B receptor a Neighboring gene transmembrane protein FAM155A-like Neighboring gene sterile alpha motif domain-containing protein 3-like Neighboring gene insulin receptor substrate 2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011334167.1 Unplaced Scaffold Reference NC01 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA ligase (ATP) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA ligation involved in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via nonhomologous end joining IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunoglobulin V(D)J recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair, DNA gap filling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA ligase IV complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of DNA-dependent protein kinase-DNA ligase 4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA ligase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Notothenia coriiceps Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NC01 Primary Assembly

Genomic

  1. NW_011334167.1 Reference NC01 Primary Assembly

    Range
    223137..228145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010789906.1 → XP_010788208.1  DNA ligase 4

    UniProtKB/TrEMBL
    A0A6I9PM49
    Conserved Domains (7) summary
    cd07968
    Location:464 → 601
    OBF_DNA_ligase_IV; The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase IV is a DNA-binding module that is part of the catalytic core unit
    cd07903
    Location:240 → 461
    Adenylation_DNA_ligase_IV; Adenylation domain of DNA Ligase IV
    smart00292
    Location:663 → 734
    BRCT; breast cancer carboxy-terminal domain
    cd00027
    Location:845 → 898
    BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
    TIGR00574
    Location:86 → 607
    dnl1; DNA ligase I, ATP-dependent (dnl1)
    pfam04675
    Location:20 → 208
    DNA_ligase_A_N; DNA ligase N terminus
    pfam11411
    Location:754 → 787
    DNA_ligase_IV; DNA ligase IV
Nucleotide Protein
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