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LATS1 large tumor suppressor kinase 1 [ Serinus canaria (Common canary) ]

Gene ID: 103820565, updated on 11-Mar-2024

Summary

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Gene symbol
LATS1
Gene description
large tumor suppressor kinase 1
See related
EnsemblRapid:ENSSCAG00000011352
Gene type
protein coding
RefSeq status
MODEL
Organism
Serinus canaria
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Fringillidae; Carduelinae; Serinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_02 current serCan2020 (GCF_022539315.1) 3 NC_066316.1 (56574895..56596554)

Chromosome 3 - NC_066316.1Genomic Context describing neighboring genes Neighboring gene katanin catalytic subunit A1 Neighboring gene protein-L-isoaspartate (D-aspartate) O-methyltransferase Neighboring gene nucleoporin 43 Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene glycosylated integral membrane protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_066316.1 Chromosome 3 Reference serCan2020 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hippo signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of organ growth IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase LATS1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022539315.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference serCan2020 Primary Assembly

Genomic

  1. NC_066316.1 Reference serCan2020 Primary Assembly

    Range
    56574895..56596554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018919929.3 → XP_018775474.1  serine/threonine-protein kinase LATS1 isoform X1

    Conserved Domains (3) summary
    cd14397
    Location:104 → 144
    UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
    pfam09770
    Location:441 → 603
    PAT1; Topoisomerase II-associated protein PAT1
    cl21453
    Location:710 → 1091
    PKc_like; Protein Kinases, catalytic domain

  2. XM_030235893.2 → XP_030091753.1  serine/threonine-protein kinase LATS1 isoform X3

    Related
    ENSSCAP00000015490.2, ENSSCAT00000017353.2
    Conserved Domains (3) summary
    cd14397
    Location:104 → 144
    UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
    pfam09770
    Location:436 → 598
    PAT1; Topoisomerase II-associated protein PAT1
    cl21453
    Location:705 → 1086
    PKc_like; Protein Kinases, catalytic domain

  3. XM_009095260.4 → XP_009093508.1  serine/threonine-protein kinase LATS1 isoform X2

    UniProtKB/TrEMBL
    A0A8C9NB79
    Related
    ENSSCAP00000015494.1, ENSSCAT00000017358.2
    Conserved Domains (3) summary
    cd14397
    Location:104 → 144
    UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
    pfam09770
    Location:440 → 602
    PAT1; Topoisomerase II-associated protein PAT1
    cl21453
    Location:709 → 1090
    PKc_like; Protein Kinases, catalytic domain

  4. XM_030235894.2 → XP_030091754.1  serine/threonine-protein kinase LATS1 isoform X4

    Conserved Domains (3) summary
    cd14397
    Location:104 → 144
    UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
    pfam09770
    Location:435 → 597
    PAT1; Topoisomerase II-associated protein PAT1
    cl21453
    Location:704 → 1085
    PKc_like; Protein Kinases, catalytic domain

  5. XM_050972251.1 → XP_050828208.1  serine/threonine-protein kinase LATS1 isoform X1

Nucleotide Protein
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