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LOC103184994 24-hydroxycholesterol 7-alpha-hydroxylase [ Callorhinchus milii (elephant shark) ]

Gene ID: 103184994, updated on 11-Mar-2024

Summary

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Gene symbol
LOC103184994
Gene description
24-hydroxycholesterol 7-alpha-hydroxylase
Gene type
protein coding
RefSeq status
MODEL
Organism
Callorhinchus milii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current IMCB_Cmil_1.0 (GCF_018977255.1) Unplaced Scaffold NW_024704744.1 (28198479..28213831)
100 previous assembly Callorhinchus_milii-6.1.3 (GCF_000165045.1) Unplaced Scaffold NW_006890159.1 (1773988..1789269)

NW_024704744.1Genomic Context describing neighboring genes Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 5 Neighboring gene regulator of calcineurin 2 Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene solute carrier family 25 member 27 Neighboring gene tumor protein p53 inducible protein 3 Neighboring gene family with sequence similarity 228 member A Neighboring gene profilin family member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Elephant shark genome provides unique insights into gnathostome evolution. Venkatesh B, et al. Nature, 2014 Jan 9. PMID 24402279, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
24-hydroxycholesterol 7-alpha-hydroxylase
Names
24-hydroxycholesterol 7-alpha-hydroxylase-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Callorhinchus milii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference IMCB_Cmil_1.0 Primary Assembly

Genomic

  1. NW_024704744.1 Reference IMCB_Cmil_1.0 Primary Assembly

    Range
    28198479..28213831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007903286.2 → XP_007901477.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X1

    Conserved Domains (1) summary
    cl12078
    Location:142 → 328
    p450; Cytochrome P450

  2. XM_007903287.2 → XP_007901478.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X2

    Conserved Domains (1) summary
    cl12078
    Location:142 → 296
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version

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