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NOX3 NADPH oxidase 3 [ Physeter catodon (sperm whale) ]

Gene ID: 102979484, updated on 10-Mar-2024

Summary

Gene symbol
NOX3
Gene description
NADPH oxidase 3
See related
Ensembl:ENSPCTG00005004723
Gene type
protein coding
RefSeq status
MODEL
Organism
Physeter catodon
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Physeteridae; Physeter
Orthologs
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Genomic context

Location:
chromosome: 10
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_04 current ASM283717v5 (GCF_002837175.3) 10 NC_041223.1 (11701862..11759903)
102 previous assembly ASM283717v2 (GCF_002837175.2) 10 NC_041223.1 (11701862..11759903)

Chromosome 10 - NC_041223.1Genomic Context describing neighboring genes Neighboring gene L-lactate dehydrogenase A-like 6B Neighboring gene transmembrane protein 242 Neighboring gene AT-rich interaction domain 1B Neighboring gene claudin 20 Neighboring gene transcription factor B1, mitochondrial

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables superoxide-generating NAD(P)H oxidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in defense response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002837175.3-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM283717v5 Primary Assembly

Genomic

  1. NC_041223.1 Reference ASM283717v5 Primary Assembly

    Range
    11701862..11759903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007106249.2XP_007106311.1  NADPH oxidase 3

    UniProtKB/TrEMBL
    A0A2Y9EPI1
    Related
    ENSPCTP00005006747.1, ENSPCTT00005007422.1
    Conserved Domains (2) summary
    cd06186
    Location:295568
    NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
    pfam01794
    Location:66217
    Ferric_reduct; Ferric reductase like transmembrane component