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APOE apolipoprotein E [ Bos mutus (wild yak) ]

Gene ID: 102276000, updated on 10-Mar-2024

Summary

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Gene symbol
APOE
Gene description
apolipoprotein E
Locus tag
M91_05707
See related
Ensembl:ENSBMUG00000019894
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos mutus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
101 current BosGru_v2.0 (GCF_000298355.1) Unplaced Scaffold NW_005394199.1 (368982..374003)

NW_005394199.1Genomic Context describing neighboring genes Neighboring gene nectin cell adhesion molecule 2 Neighboring gene 60S ribosomal protein L15-like Neighboring gene translocase of outer mitochondrial membrane 40 Neighboring gene 40S ribosomal protein S17-like Neighboring gene apolipoprotein C4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005394199.1 Unplaced Scaffold Reference BosGru_v2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yak genome and adaptation to life at high altitude. Qiu Q, et al. Nat Genet, 2012 Jul 1. PMID 22751099

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables low-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables very-low-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipoprotein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of amyloid-beta clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of intermediate-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apolipoprotein E

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos mutus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BosGru_v2.0 Primary Assembly

Genomic

  1. NW_005394199.1 Reference BosGru_v2.0 Primary Assembly

    Range
    368982..374003
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014479647.1 → XP_014335133.1  apolipoprotein E isoform X3

    UniProtKB/TrEMBL
    L8I9E0
    Conserved Domains (1) summary
    pfam01442
    Location:85 → 272
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  2. XM_005900307.2 → XP_005900369.1  apolipoprotein E isoform X3

    See identical proteins and their annotated locations for XP_005900369.1

    UniProtKB/TrEMBL
    L8I9E0
    Related
    ENSBMUP00000026487.1, ENSBMUT00000030498.1
    Conserved Domains (1) summary
    pfam01442
    Location:85 → 272
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  3. XM_014479654.1 → XP_014335140.1  apolipoprotein E isoform X4

    Conserved Domains (1) summary
    pfam01442
    Location:71 → 233
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  4. XM_014479651.1 → XP_014335137.1  apolipoprotein E isoform X3

    UniProtKB/TrEMBL
    L8I9E0
    Conserved Domains (1) summary
    pfam01442
    Location:85 → 272
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  5. XM_014479652.1 → XP_014335138.1  apolipoprotein E isoform X3

    UniProtKB/TrEMBL
    L8I9E0
    Related
    ENSBMUP00000026490.1, ENSBMUT00000030501.1
    Conserved Domains (1) summary
    pfam01442
    Location:85 → 272
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  6. XM_014479645.1 → XP_014335131.1  apolipoprotein E isoform X1

    Conserved Domains (1) summary
    pfam01442
    Location:118 → 305
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  7. XM_014479653.1 → XP_014335139.1  apolipoprotein E isoform X3

    UniProtKB/TrEMBL
    L8I9E0
    Conserved Domains (1) summary
    pfam01442
    Location:85 → 272
    Apolipoprotein; Apolipoprotein A1/A4/E domain

  8. XM_014479646.1 → XP_014335132.1  apolipoprotein E isoform X2

    Conserved Domains (1) summary
    pfam01442
    Location:98 → 285
    Apolipoprotein; Apolipoprotein A1/A4/E domain
Nucleotide Protein
Heading Accession and Version

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