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TOP3A DNA topoisomerase III alpha [ Pseudopodoces humilis (Tibetan ground-tit) ]

Gene ID: 102113924, updated on 10-Mar-2024

Summary

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Gene symbol
TOP3A
Gene description
DNA topoisomerase III alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Pseudopodoces humilis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Paridae; Pseudopodoces
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
101 current PseHum1.0 (GCF_000331425.1) Unplaced Scaffold NW_005087569.1 (14089778..14101197, complement)

NW_005087569.1Genomic Context describing neighboring genes Neighboring gene FLII actin remodeling protein Neighboring gene mitochondrial elongation factor 2 Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene serine hydroxymethyltransferase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005087569.1 Unplaced Scaffold Reference PseHum1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type I (single strand cut, ATP-independent) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 3-alpha
Names
topoisomerase (DNA) III alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pseudopodoces humilis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PseHum1.0 Primary Assembly

Genomic

  1. NW_005087569.1 Reference PseHum1.0 Primary Assembly

    Range
    14089778..14101197 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014252793.1 → XP_014108268.1  DNA topoisomerase 3-alpha

    Conserved Domains (5) summary
    cd03362
    Location:35 → 193
    TOPRIM_TopoIA_TopoIII; TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving ...
    COG0550
    Location:35 → 648
    TopA; DNA topoisomerase IA [Replication, recombination and repair]
    cd00186
    Location:202 → 606
    TOP1Ac; DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA ...
    pfam01396
    Location:655 → 693
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger
    pfam06839
    Location:908 → 952
    zf-GRF; GRF zinc finger

  2. XM_005523063.2 → XP_005523120.2  DNA topoisomerase 3-alpha

    Conserved Domains (5) summary
    cd03362
    Location:35 → 193
    TOPRIM_TopoIA_TopoIII; TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving ...
    COG0550
    Location:35 → 648
    TopA; DNA topoisomerase IA [Replication, recombination and repair]
    cd00186
    Location:202 → 606
    TOP1Ac; DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA ...
    pfam01396
    Location:655 → 693
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger
    pfam06839
    Location:908 → 952
    zf-GRF; GRF zinc finger
Nucleotide Protein
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