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EIF1 eukaryotic translation initiation factor 1 [ Homo sapiens (human) ]

Gene ID: 10209, updated on 6-Sep-2017
Official Symbol
EIF1provided by HGNC
Official Full Name
eukaryotic translation initiation factor 1provided by HGNC
Primary source
HGNC:HGNC:3249
See related
Ensembl:ENSG00000173812 Vega:OTTHUMG00000133492
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
A121; ISO1; SUI1; EIF-1; EIF1A
Orthologs
Location:
17q21.2
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 17 NC_000017.11 (41688875..41691646)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (39845127..39847898)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene keratin 17 Neighboring gene keratin 42 pseudogene Neighboring gene RNA, 5S ribosomal pseudogene 442 Neighboring gene gastrin

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • RNA transport, organism-specific biosystem (from KEGG)
    RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
  • RNA transport, conserved biosystem (from KEGG)
    RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
  • Translation Factors, organism-specific biosystem (from WikiPathways)
    Translation Factors, organism-specific biosystemProtein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, ...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
translation factor activity, RNA binding TAS
Traceable Author Statement
more info
PubMed 
translation initiation factor activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
dosage compensation by inactivation of X chromosome IEA
Inferred from Electronic Annotation
more info
 
regulation of translational initiation IDA
Inferred from Direct Assay
more info
PubMed 
response to stress NAS
Non-traceable Author Statement
more info
PubMed 
translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
eukaryotic translation initiation factor 1
Names
protein translation factor SUI1 homolog
sui1iso1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005801.3NP_005792.1  eukaryotic translation initiation factor 1

    See identical proteins and their annotated locations for NP_005792.1

    Status: VALIDATED

    Source sequence(s)
    AA159721, BC005118, BU165055
    Consensus CDS
    CCDS11403.1
    UniProtKB/Swiss-Prot
    P41567
    UniProtKB/TrEMBL
    Q6IAV3
    Related
    ENSP00000419449.1, OTTHUMP00000164728, ENST00000469257.1, OTTHUMT00000257390
    Conserved Domains (1) summary
    cl00229
    Location:3113
    eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p7 Primary Assembly

    Range
    41688875..41691646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018928.2 Alternate CHM1_1.1

    Range
    40080633..40083404
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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