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Dmd dystrophin [ Chinchilla lanigera (long-tailed chinchilla) ]

Gene ID: 102027455, updated on 10-Mar-2024

Summary

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Gene symbol
Dmd
Gene description
dystrophin
See related
Ensembl:ENSCLAG00000000730
Gene type
protein coding
RefSeq status
MODEL
Organism
Chinchilla lanigera
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Chinchillidae; Chinchilla
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
81
Annotation release Status Assembly Chr Location
101 current ChiLan1.0 (GCF_000276665.1) Unplaced Scaffold NW_004955535.1 (1283084..3297015)

NW_004955535.1Genomic Context describing neighboring genes Neighboring gene actin-binding LIM protein 3 pseudogene Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 pseudogene Neighboring gene ferritin heavy chain pseudogene Neighboring gene TGF-beta activated kinase 1 (MAP3K7) binding protein 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004955535.1 Unplaced Scaffold Reference ChiLan1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in synaptic signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dystrophin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chinchilla lanigera Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ChiLan1.0 Primary Assembly

Genomic

  1. NW_004955535.1 Reference ChiLan1.0 Primary Assembly

    Range
    1283084..3297015
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013507710.1 → XP_013363164.1  dystrophin isoform X1

    UniProtKB/TrEMBL
    A0A8C2UN70
    Related
    ENSCLAP00000000939.1, ENSCLAT00000000976.1
    Conserved Domains (10) summary
    COG1340
    Location:1705 → 1980
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00014
    Location:16 → 119
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:345 → 559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:3053 → 3082
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:3305 → 3353
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    pfam00435
    Location:2928 → 3034
    Spectrin; Spectrin repeat
    pfam09068
    Location:3083 → 3201
    EF-hand_2; EF hand
    pfam09069
    Location:3205 → 3296
    EF-hand_3; EF-hand
    pfam16769
    Location:3482 → 3665
    MCM3AP_GANP; MCM3AP domain of GANP
    cl02488
    Location:1616 → 1773
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  2. XM_005410485.2 → XP_005410542.2  dystrophin isoform X2

    Conserved Domains (8) summary
    cd00176
    Location:10 → 204
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:330 → 359
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:582 → 630
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    pfam00435
    Location:205 → 311
    Spectrin; Spectrin repeat
    pfam01442
    Location:165 → 311
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    pfam09068
    Location:360 → 478
    EF-hand_2; EF hand
    pfam09069
    Location:482 → 573
    EF-hand_3; EF-hand
    pfam16769
    Location:759 → 942
    MCM3AP_GANP; MCM3AP domain of GANP

  3. XM_005410486.1 → XP_005410543.1  dystrophin isoform X3

    Conserved Domains (4) summary
    cd02334
    Location:243 → 291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    pfam09068
    Location:21 → 139
    EF-hand_2; EF hand
    pfam09069
    Location:143 → 234
    EF-hand_3; EF-hand
    pfam16769
    Location:420 → 613
    MCM3AP_GANP; MCM3AP domain of GANP

  4. XM_005410487.1 → XP_005410544.1  dystrophin isoform X4

    Conserved Domains (4) summary
    cd02334
    Location:243 → 291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    pfam09068
    Location:21 → 139
    EF-hand_2; EF hand
    pfam09069
    Location:143 → 234
    EF-hand_3; EF-hand
    pfam16769
    Location:407 → 600
    MCM3AP_GANP; MCM3AP domain of GANP

  5. XM_005410488.1 → XP_005410545.1  dystrophin isoform X5

    UniProtKB/TrEMBL
    A0A8C2UHA6
    Related
    ENSCLAP00000000942.1, ENSCLAT00000000979.1
    Conserved Domains (4) summary
    cd02334
    Location:243 → 291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    pfam09068
    Location:21 → 139
    EF-hand_2; EF hand
    pfam09069
    Location:143 → 234
    EF-hand_3; EF-hand
    pfam16769
    Location:420 → 603
    MCM3AP_GANP; MCM3AP domain of GANP

  6. XM_005410489.1 → XP_005410546.1  dystrophin isoform X6

    Conserved Domains (4) summary
    cd02334
    Location:243 → 291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    pfam09068
    Location:21 → 139
    EF-hand_2; EF hand
    pfam09069
    Location:143 → 234
    EF-hand_3; EF-hand
    pfam16769
    Location:407 → 590
    MCM3AP_GANP; MCM3AP domain of GANP
Nucleotide Protein
Heading Accession and Version

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