U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Champ1 chromosome alignment maintaining phosphoprotein 1 [ Mus musculus (house mouse) ]

Gene ID: 101994, updated on 25-Oct-2022

Summary

Official Symbol
Champ1provided by MGI
Official Full Name
chromosome alignment maintaining phosphoprotein 1provided by MGI
Primary source
MGI:MGI:1196398
See related
Ensembl:ENSMUSG00000047710 AllianceGenome:MGI:1196398
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp828; Znf828; mKIAA1802; D8Ertd457e; D8Ertd569e
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in attachment of spindle microtubules to kinetochore and protein localization to organelle. Predicted to be located in Flemming body; kinetochore; and nuclear body. Predicted to be active in nucleoplasm and spindle. Is expressed in genitourinary system and liver. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 40. Orthologous to human CHAMP1 (chromosome alignment maintaining phosphoprotein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 12.3), CNS E14 (RPKM 11.6) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Champ1 in Genome Data Viewer
Location:
8 A1.1; 8 6.4 cM
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (13919641..13931639)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (13869641..13881639)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene SUMO/sentrin specific peptidase 2-like 2A Neighboring gene predicted gene, 53400 Neighboring gene predicted gene, 24698 Neighboring gene coordinator of PRMT5, differentiation stimulator Neighboring gene interferon induced transmembrane protein 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (5) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in attachment of mitotic spindle microtubules to kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in attachment of mitotic spindle microtubules to kinetochore ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein localization to kinetochore ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein localization to microtubule ISO
Inferred from Sequence Orthology
more info
 
involved_in sister chromatid biorientation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in sister chromatid biorientation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Flemming body ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
located_in condensed chromosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
is_active_in spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
chromosome alignment-maintaining phosphoprotein 1
Names
zinc finger protein 828

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363455.1NP_001350384.1  chromosome alignment-maintaining phosphoprotein 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC139186
    Consensus CDS
    CCDS22116.1
    UniProtKB/Swiss-Prot
    Q6ZPI1
    Related
    ENSMUSP00000120117.3, ENSMUST00000128557.3
    Conserved Domains (2) summary
    sd00017
    Location:730750
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl26464
    Location:109466
    Atrophin-1; Atrophin-1 family
  2. NM_181854.2NP_862902.1  chromosome alignment-maintaining phosphoprotein 1

    See identical proteins and their annotated locations for NP_862902.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AK132164, AK133990, BX633091, CJ077618
    Consensus CDS
    CCDS22116.1
    UniProtKB/Swiss-Prot
    Q6ZPI1, Q8K327
    UniProtKB/TrEMBL
    A0A140T8S5
    Related
    ENSMUSP00000057270.8, ENSMUST00000051870.8
    Conserved Domains (2) summary
    sd00017
    Location:730750
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl26464
    Location:109466
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    13919641..13931639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)