U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Itih2 inter-alpha-trypsin inhibitor heavy chain 2 [ Mesocricetus auratus (golden hamster) ]

Gene ID: 101837243, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Itih2
Gene description
inter-alpha-trypsin inhibitor heavy chain 2
See related
EnsemblRapid:ENSMAUG00000012495
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mesocricetus auratus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Mesocricetus
Also known as
ITI-HC2
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
103 current BCM_Maur_2.0 (GCF_017639785.1) Unplaced Scaffold NW_024429196.1 (27821691..27856524, complement)
102 previous assembly MesAur1.0 (GCF_000349665.1) Unplaced Scaffold NW_004801633.1 (3028193..3058891, complement)

NW_024429196.1Genomic Context describing neighboring genes Neighboring gene ATP synthase F1 subunit gamma Neighboring gene Kin17 DNA and RNA binding protein Neighboring gene uncharacterized LOC110341184 Neighboring gene inter-alpha-trypsin inhibitor heavy chain 5

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular cloning and sequencing of cDNAs encoding three heavy-chain precursors of the inter-alpha-trypsin inhibitor in Syrian hamster: implications for the evolution of the inter-alpha-trypsin inhibitor heavy chain family. Nakatani T, et al. J Biochem, 1997 Jul. PMID 9276673
  2. Inter-alpha-trypsin inhibitor and its related proteins in Syrian hamster urine and plasma. Yamamoto T, et al. J Biochem, 1996 Jul. PMID 8864857
  3. Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters. Ying B, et al. Virology, 2015 Nov. PMID 26319212, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hyaluronan metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
inter-alpha-trypsin inhibitor heavy chain H2
Names
ITI heavy chain H2
Inter-alpha-inhibitor heavy chain 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001281662.1 → NP_001268591.1  inter-alpha-trypsin inhibitor heavy chain H2 precursor

    See identical proteins and their annotated locations for NP_001268591.1

    Status: PROVISIONAL

    Source sequence(s)
    D89286
    UniProtKB/Swiss-Prot
    P97279
    UniProtKB/TrEMBL
    A0A1U7Q2C1
    Related
    ENSMAUP00000044192.1, ENSMAUT00000079848.1
    Conserved Domains (4) summary
    smart00609
    Location:56 → 185
    VIT; Vault protein Inter-alpha-Trypsin domain
    cd01461
    Location:307 → 488
    vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
    TIGR03788
    Location:80 → 629
    marine_srt_targ; marine proteobacterial sortase target protein
    pfam06668
    Location:736 → 921
    ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus

RefSeqs of Annotated Genomes: Mesocricetus auratus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Maur_2.0 Primary Assembly

Genomic

  1. NW_024429196.1 Reference BCM_Maur_2.0 Primary Assembly

    Range
    27821691..27856524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P97279.1 GenPept UniProtKB/Swiss-Prot:P97279

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.