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Ppp4r3a protein phosphatase 4 regulatory subunit 3A [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101710488, updated on 8-Mar-2024

Summary

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Gene symbol
Ppp4r3a
Gene description
protein phosphatase 4 regulatory subunit 3A
Locus tag
GW7_05563
See related
Ensembl:ENSHGLG00000016246
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Also known as
Smek1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (11160253..11197264)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene cation channel sperm associated auxiliary subunit beta Neighboring gene protein CASC4 pseudogene Neighboring gene citrate synthase, mitochondrial pseudogene Neighboring gene coiled-coil domain containing 88C Neighboring gene G protein-coupled receptor 68

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein phosphatase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of protein phosphatase 4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein phosphatase 4 regulatory subunit 3A
Names
SMEK homolog 1, suppressor of mek1
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    11160253..11197264
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004837061.3 → XP_004837118.1  serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1

    UniProtKB/TrEMBL
    G5AZZ9
    Related
    ENSHGLP00000022779.1, ENSHGLT00000022993.1
    Conserved Domains (2) summary
    pfam04802
    Location:166 → 357
    SMK-1; Component of IIS longevity pathway SMK-1
    cl17171
    Location:7 → 65
    PH-like; Pleckstrin homology-like domain

  2. XM_004837062.3 → XP_004837119.1  serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X2

    UniProtKB/TrEMBL
    A0A0P6J4Y1
    Conserved Domains (2) summary
    pfam04802
    Location:166 → 357
    SMK-1; Component of IIS longevity pathway SMK-1
    cl17171
    Location:7 → 65
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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