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Prdx6 peroxiredoxin 6 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101696758, updated on 8-Mar-2024

Summary

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Gene symbol
Prdx6
Gene description
peroxiredoxin 6
Locus tag
GW7_21572
See related
Ensembl:ENSHGLG00000007539
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624771.1 (8282622..8293799, complement)

NW_004624771.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 45 Neighboring gene testis expressed 50 Neighboring gene solute carrier family 9 member C2 (putative) Neighboring gene KATNB1-like protein 1 pseudogene Neighboring gene coiled-coil domain-containing protein 175-like Neighboring gene ubiquitin-conjugating enzyme E2 variant 1 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624771 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peroxiredoxin-6
Names
Peroxiredoxin-6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624771.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    8282622..8293799 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004853421.3 → XP_004853478.1  peroxiredoxin-6

    See identical proteins and their annotated locations for XP_004853478.1

    UniProtKB/TrEMBL
    G5ART4
    Related
    ENSHGLP00000010510.1, ENSHGLT00000010627.1
    Conserved Domains (2) summary
    COG0450
    Location:5 → 200
    AhpC; Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin) [Defense mechanisms]
    cd03016
    Location:7 → 222
    PRX_1cys; Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by ...
Nucleotide Protein
Heading Accession and Version

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