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DUSP5 dual specificity phosphatase 5 [ Trichechus manatus latirostris (Florida manatee) ]

Gene ID: 101346474, updated on 8-Mar-2024

Summary

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Gene symbol
DUSP5
Gene description
dual specificity phosphatase 5
See related
EnsemblRapid:ENSTMLG00000015498
Gene type
protein coding
RefSeq status
MODEL
Organism
Trichechus manatus latirostris (sub-species: latirostris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_01 current TriManLat1.0 (GCF_000243295.1) Unplaced Scaffold NW_004443967.1 (1141787..1155378)

NW_004443967.1Genomic Context describing neighboring genes Neighboring gene MAX interactor 1, dimerization protein Neighboring gene survival motor neuron domain containing 1 Neighboring gene structural maintenance of chromosomes 3 Neighboring gene cyclin-H pseudogene Neighboring gene RNA binding motif protein 20

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004443967 Unplaced Scaffold Reference TriManLat1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoderm formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000243295.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TriManLat1.0 Primary Assembly

Genomic

  1. NW_004443967.1 Reference TriManLat1.0 Primary Assembly

    Range
    1141787..1155378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004374949.2 → XP_004375006.1  dual specificity protein phosphatase 5

    UniProtKB/TrEMBL
    A0A2Y9DIT2
    Related
    ENSTMLP00000021692.1, ENSTMLT00000023259.1
    Conserved Domains (3) summary
    COG2453
    Location:171 → 318
    CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]
    cd01446
    Location:5 → 140
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    pfam00782
    Location:186 → 314
    DSPc; Dual specificity phosphatase, catalytic domain
Nucleotide Protein
Heading Accession and Version

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