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celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 [ Oryzias latipes (Japanese medaka) ]

Gene ID: 101165226, updated on 8-Mar-2024

Summary

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Gene symbol
celsr2
Gene description
cadherin, EGF LAG seven-pass G-type receptor 2
See related
EnsemblRapid:ENSORLG00000000182
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryzias latipes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
Orthologs
human zebrafish all
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Genomic context

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See celsr2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
34
Annotation release Status Assembly Chr Location
103 current ASM223467v1 (GCF_002234675.1) 5 NC_019863.2 (2111201..2200596)
102 previous assembly ASM31367v1 (GCF_000313675.1) 5 NC_019863.1 (236823..329405)

Chromosome 5 - NC_019863.2Genomic Context describing neighboring genes Neighboring gene mitochondrial contact site and cristae organizing system subunit 10 Neighboring gene capping actin protein of muscle Z-line subunit beta Neighboring gene uncharacterized LOC110015089 Neighboring gene dual serine/threonine and tyrosine protein kinase Neighboring gene NUAK family, SNF1-like kinase, 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cadherin EGF LAG seven-pass G-type receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM223467v1 Primary Assembly

Genomic

  1. NC_019863.2 Reference ASM223467v1 Primary Assembly

    Range
    2111201..2200596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023954719.1 → XP_023810487.1  cadherin EGF LAG seven-pass G-type receptor 2

    UniProtKB/TrEMBL
    A0A3P9M0G3
    Related
    ENSORLP00000051392.1, ENSORLT00000049266.1
    Conserved Domains (11) summary
    smart00303
    Location:2411 → 2463
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:899 → 997
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:2066 → 2124
    HormR; Domain present in hormone receptors
    smart00179
    Location:1428 → 1462
    EGF_CA; Calcium-binding EGF-like domain
    smart00180
    Location:2017 → 2062
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00054
    Location:1676 → 1706
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1465 → 1648
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1925 → 1958
    EGF; EGF-like domain
    pfam16489
    Location:2144 → 2385
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd15992
    Location:2468 → 2722
    7tmB2_CELSR2; Cadherin EGF LAG seven-pass G-type receptor 2, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl22855
    Location:1967 → 2059
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
Nucleotide Protein
Heading Accession and Version

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