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TINAG tubulointerstitial nephritis antigen [ Felis catus (domestic cat) ]

Gene ID: 101087743, updated on 8-Mar-2024

Summary

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Official Symbol
TINAG
Official Full Name
tubulointerstitial nephritis antigen
Primary source
VGNC:VGNC:66195
See related
EnsemblRapid:ENSFCTG00005009253
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See TINAG in Genome Data Viewer
Location:
chromosome: B2
Exon count:
12
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) B2 NC_058372.1 (51696258..51779239)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) B2 NC_018727.3 (54585444..54668597)

Chromosome B2 - NC_058372.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 1 Neighboring gene muscular LMNA interacting protein Neighboring gene small nucleolar RNA SNORA51 Neighboring gene transmembrane protein 258-like Neighboring gene family with sequence similarity 83 member B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tubulointerstitial nephritis antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058372.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    51696258..51779239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019830738.2 → XP_019686297.1  tubulointerstitial nephritis antigen isoform X2

    Conserved Domains (3) summary
    pfam01033
    Location:59 → 101
    Somatomedin_B; Somatomedin B domain
    cl17735
    Location:117 → 164
    VWC; von Willebrand factor type C domain
    cl23744
    Location:215 → 358
    Peptidase_C1; C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some ...

  2. XM_006931811.3 → XP_006931873.1  tubulointerstitial nephritis antigen isoform X1

    UniProtKB/TrEMBL
    M3WAV9
    Related
    ENSFCTP00005016767.1, ENSFCTT00005025764.1
    Conserved Domains (3) summary
    smart00215
    Location:117 → 164
    VWC_out; von Willebrand factor (vWF) type C domain
    cd02620
    Location:215 → 464
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    pfam01033
    Location:59 → 101
    Somatomedin_B; Somatomedin B domain
Nucleotide Protein
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