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SPHK1 sphingosine kinase 1 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100977890, updated on 11-Mar-2024

Summary

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Gene symbol
SPHK1
Gene description
sphingosine kinase 1
See related
Ensembl:ENSPPAG00000024352
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 19 NC_073268.2 (92424277..92430882)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 17 NC_073266.1 (97251477..97256099)

Chromosome 19 - NC_073268.2Genomic Context describing neighboring genes Neighboring gene phosphoribosyl pyrophosphate synthetase associated protein 1 Neighboring gene small nucleolar RNA U13 Neighboring gene U6 spliceosomal RNA Neighboring gene ubiquitin conjugating enzyme E2 O Neighboring gene aralkylamine N-acetyltransferase Neighboring gene rhomboid 5 homolog 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables D-erythro-sphingosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingosine kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073268.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    92424277..92430882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034942938.4 → XP_034798829.1  sphingosine kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A2R8ZTA2
    Conserved Domains (1) summary
    PLN02958
    Location:11 → 345
    PLN02958; diacylglycerol kinase/D-erythro-sphingosine kinase

  2. XM_003813239.5 → XP_003813287.2  sphingosine kinase 1 isoform X1

    See identical proteins and their annotated locations for XP_003813287.2

    UniProtKB/TrEMBL
    A0A2R8ZMC3
    Related
    ENSPPAP00000006098.1
    Conserved Domains (1) summary
    cl27661
    Location:97 → 431
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
Nucleotide Protein
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