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DMGDH dimethylglycine dehydrogenase [ Sarcophilus harrisii (Tasmanian devil) ]

Gene ID: 100931635, updated on 8-Mar-2024

Summary

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Gene symbol
DMGDH
Gene description
dimethylglycine dehydrogenase
See related
Ensembl:ENSSHAG00000014992
Gene type
protein coding
RefSeq status
MODEL
Organism
Sarcophilus harrisii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
17
Annotation release Status Assembly Chr Location
103 current mSarHar1.11 (GCF_902635505.1) 1 NC_045426.1 (161619694..161722749)
102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 2 Unlocalized Scaffold NW_003823184.1 (1649640..1769570)

Chromosome 1 - NC_045426.1Genomic Context describing neighboring genes Neighboring gene junction mediating and regulatory protein, p53 cofactor Neighboring gene betaine--homocysteine S-methyltransferase Neighboring gene betaine--homocysteine S-methyltransferase 2 Neighboring gene arylsulfatase B Neighboring gene LHFPL tetraspan subfamily member 2 Neighboring gene eukaryotic translation initiation factor 3 subunit L pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dimethylglycine dehydrogenase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSarHar1.11 Primary Assembly

Genomic

  1. NC_045426.1 Reference mSarHar1.11 Primary Assembly

    Range
    161619694..161722749
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023495798.2 → XP_023351566.1  dimethylglycine dehydrogenase, mitochondrial isoform X2

    Conserved Domains (3) summary
    COG0404
    Location:392 → 785
    GcvT; Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]
    COG0665
    Location:3 → 363
    DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
    pfam16350
    Location:349 → 398
    FAO_M; FAD dependent oxidoreductase central domain

  2. XM_003759434.4 → XP_003759482.1  dimethylglycine dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    G3WQF5
    Related
    ENSSHAP00000017660.2, ENSSHAT00000017805.2
    Conserved Domains (6) summary
    COG0404
    Location:470 → 863
    GcvT; Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]
    COG0665
    Location:53 → 441
    DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
    pfam01571
    Location:488 → 751
    GCV_T; Aminomethyltransferase folate-binding domain
    pfam08669
    Location:759 → 851
    GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
    pfam16350
    Location:424 → 476
    FAO_M; FAD dependent oxidoreductase central domain
    cl21454
    Location:52 → 96
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version

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