Conserved Protein Domain Family
DadA

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COG0665: DadA 
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 223737
View PSSM: COG0665
Aligned: 225 rows
Threshold Bit Score: 34.1048
Threshold Setting Gi: 1175886
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17988866 140 GSQQADVVVIGGGYTGLSAAYHLAKQGtDVVLIEAARLGDGASGRNGGQFGTGQRTWAEDLETEYGYERAKALFNVAEEA 219
gi 22654194 243 slknkKVAIIGAGISSAVLAYELSLRGfEIDIFEKHLELGKGASGNESGILSSLILKP----KVNLGEFSELSFIEASRF 318
gi 22654196 262 SSK-REVAIIGGGIASALLSLALLRRGwQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNGFTFARRLYDSL 340
gi 22654196 262 SSK-REVAIIGGGIASALLSLALLRRGwQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNGFTFARRLYDSL 340
gi 1175886      --------------------------------------------------------------------------------
gi 22654189 260 LTENADIALIGGGIASVFSALSLLERGaKVTVYCEDNSLAANASGNKQGAFYPQLSDDDLRYIRFYIHAFAYGKQRFNWA 339
gi 22654204 262 SEK-RETAIIGGGIASALLSLALLRRGwQVTLYCADDQPAQGASGNRQGALYPLLSKHDAAINRFFPTAFTFARRLYDAL 340
gi 22654207 263 thglqevaiigggiasatlattlaRRGvAVTLYCADEKPAQGASGNRQGAVYPLLSGDHNAVSRVFAPAFLFARQWIEQA 342
gi 22654210 261 ATRCDDIAIIGGGIVSALTALALQRRGaVVTLYCADAQPAQGASGNRQGALYPLLNGKNDALETFFTSAFTFARRQYDQL 340
gi 20140544 262 SSK-REAAIIGGGIASALLSLALLRRGwQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQL 340
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17988866 220 KSYL-LAFAEEHAIDMEYVQG-HisvvHKPRYLKSYERHVEQMasrfnypHQRFLDRAETAELLGTSRYHGGVYDSATGH 297
gi 22654194 319 YRQI-LDLEFKGVVEFAHNDL------MQERFDTQRENVLFK---------ISKNQAFLEEGGVIFP--KKLVKNLFEKS 380
gi 22654196 341 PVK----FDHDWCGVTQLGWDeK----SQHKIAQMLSMDLPEE-------LAVAVEANAVEQITGVTTNCSGITYPQGGW 405
gi 22654196 341 PVK----FDHDWCGVTQLGWDeK----SQHKIAQMLSMDLPEE-------LAVAVEANAVEQITGVTTNCSGITYPQGGW 405
gi 1175886      --------------------------------------------------------------------------------
gi 22654189 340 IEQGiT-FEHDFCGVALCAYDaK----SAVKLAKISALQLPPS-------LYQPLSQQALSEQVGLPLPCDGGFIAQGAW 407
gi 22654204 341 PVS----FDHDWCGVTQLGWDeK----SQQKIAQMLSLALPAG-------LASALNAEEAEQAVGVTTRCGGITYPAGGW 405
gi 22654207 343 AEQIn--FDHDWCGVTQLMWDeK----ATDKLKSMLEGNFPTQ-------LVHGLSAEQTNQQVGVPVDKASVHYPLGGW 409
gi 22654210 341 LEQGiA-FDHQWCGVSQLAFDdK----SRGKIEKMLHTQWPVE-------FAEAMSREQLSELAGLDCAHDGIHYPAGGW 408
gi 20140544 341 PVK----FDHDWCGVTQLGWDeK----SQHKIAQMLSMDLPAE-------LAVAVEANAVEQITGVATNCSGITYPQGGW 405
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17988866 298 IHPMKLLIGTAKAAHTAGAKLFE-DTKATKIST--AsGRVEVETTRGTiRARHAFIAVNAYGGR----LEp---VSASHV 367
gi 22654194 381 KACIYFNHEFQAYKFENGCFSLKfKNDVVKSDYa-----VLIYAMGAD-AKDFVFYDEMKLSKVrgqvTHl--kPFLDTP 452
gi 22654196 406 LCPAELTRNVLELAQQQG-LQIYyQYQLQDLSRkdDcWLLTFAGDQQAt-HSVVVLANGHQISRfsqtSSlpvySVAGQV 483
gi 22654196 406 LCPAELTRNVLELAQQQG-LQIYyQYQLQDLSRkdDcWLLTFAGDQQAt-HSVVVLANGHQISRfsqtSSlpvySVAGQV 483
gi 1175886      --------------------------------------------------------------------------------
gi 22654189 408 LSPQQFVQNTFDFLATRG-VIIKtQQKITALERqtThWLLTTEQGDSFk-HQVVVLANGHKLTQfrqtEHlpvyPVRGQV 485
gi 22654204 406 LCPEQLTRAVIALATEQG-LQTRfRHTLTSLVAqeSrWQLRFTSGETAs-HETVVLANGHQINRfdqtQPlpvyAVGGQV 483
gi 22654207 410 LSPAELTQGLIHLLEQQGKLTAHyQTPIDALTWqpEtQLWQLRSGDTLmsHQCVVIASGHQFDSlsqtAElplgKVKGQV 489
gi 22654210 409 LCPSDLTHALMMLAQQNG-MTCHyQHELQRLKRidSqWQLTFGQSQAAkhHATVILATGHRLPEweqtHHlplsAVRGQV 487
gi 20140544 406 LCPAELTRNVLELAQQQG-LQIYyQYQLQNLSRkdDcWLLNFAGDQQAt-HSVVVLANGHQISRfsqtSTlpvySVAGQV 483
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17988866 368 MPIRSFIGATAPLG-DDS-PVIpgg-----esVDDSRFVVRYFRRS------KDGRLLFGGREAYTa----DNP-----R 425
gi 22654194 453 FPLSSKAYICPVKDdLQViG------------ASYDRLNASLESKE------EDDKQNIENIADFMdk--nTKLeiigsK 512
gi 22654196 484 SHIPTTPELAKLKQvLCYdGYLtpqnpanqhhCIGASYHRGSEETAysednqQQNRQRLIDCFPHAqwaktVDVskkeaR 563
gi 22654196 484 SHIPTTPELAKLKQvLCYdGYLtpqnpanqhhCIGASYHRGSEETAysednqQQNRQRLIDCFPHAqwaktVDVskkeaR 563
gi 1175886    1 -----------------------------------------------------------------------MDTsdnlaR 9
gi 22654189 486 SEIATSTELSKLKAvICYdGYLtpkaa-sqthCLGASHLRDNAERAfslqeqQENQQKIQTNLASVdwvneVDTrnnqaR 564
gi 22654204 484 SHIPTTPALSALRQvLCYdGYLtpqnphnqqhCIGASYHRGDESTVwreedqRQNRQRLLDCFPDAkwateVDVsgnsaR 563
gi 22654207 490 SHIPTTETLSKINSvLCYdGYMtpvsqqngyhCIGASYDRQHLDATfdpqaqHENAQKLIHCLPEQtwpleVDVsgnqsR 569
gi 22654210 488 SHIPTTPVLSQLQQvLCYdGYLtpvnpanqhhCIGASYQRGDIATDfrlteqQENRERLLRCLPQVswpqqVDVsdnqaR 567
gi 20140544 484 SHIPTTPELAELKQvLCYdGYLtpqnpanqhhCIGASYHRGSEDTAyseddqQQNRQRLIDCFPQAqwakeVDVsdkeaR 563
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17988866 426 D-------ISAHIRRQITEIYPALENVEITH----------AWGGSVGIT-MPRQPFVREvM---PGVISAGGYSGHGVM 484
gi 22654194 513 Vg-------FRSYSSDRFMIVGNAYDEAFYKe---------EYKALLWTKnKEQKPAKMS-----CNLYFNFAHGSRGFS 571
gi 22654196 564 CgvrcatrDHLPMVGNVPDYEATLVEYASLAe--------qKDKAVSAPVfDDLFMFAAL-GsrgLCSAPLCAEILAAQM 634
gi 22654196 564 CgvrcatrDHLPMVGNVPDYEATLVEYASLAe--------qKDKAVSAPVfDDLFMFAAL-GsrgLCSAPLCAEILAAQM 634
gi 1175886   10 VgircsvrDLAPMVGNVPHFEQQQADYYNLFnlr-----rrKQPIQSAANfQNLFLIAAL-GsrgLTSAPLLGETLASII 83
gi 22654189 565 IgircsvrDRIPMLGNVPDFEQQLSDYHNLYnlr-----rrKHAIKHAALhPNLFLIGAL-GsrgLTSAPLLAETLASLI 638
gi 22654204 564 CgvrcatrDHLPMVGNVPDYHATLTHYADLAd--------nKTSAAPAPVyPGLFMLGAL-GsrgLCSAPLCAEILAAQM 634
gi 22654207 570 QgvrcvsrDHLPFVGNVGEFSKITEQYRDLAq---------QHQAEPIALyPQLYALVGL-GsrgLSSAPLMAELLASQM 639
gi 22654210 568 CgvrcairDHLPMVGAVPDYAATLAQYQDLSrriqhggeseVNDIAVAPVwPELFMVGGL-GsrgLCSAPLVAEILAAQM 646
gi 20140544 564 CgvrcatrDHLPMVGNVPDYEATLVEYASLAe--------qKDEAVSAPVfDDLFMFAAL-GsrgLCSAPLCAEILAAQM 634
                       410       420       430
                ....*....|....*....|....*....|....*....
gi 17988866 485 LANYVGKLYADTLAG-RREKLKLFEELRIp-pFPGGRTF 521
gi 22654194 572 TSVLAARYLCALINNePLCLEKKYIHAIHparFLIRKLK 610
gi 22654196 635 SDEPIPMDASTLAALnPNRLWVRKLLKGK---AVKAG-- 668
gi 22654196 635 SDEPIPMDASTLAALnPNRLWVRKLLKGK---AVKAG-- 668
gi 1175886   84 YGEPLPISEGILHNLsANRAWVKKWLKGS---KVE---- 115
gi 22654189 639 YHEPLPLSEDILHQLnANRSWIRKLLKGS---QVKQG-- 672
gi 22654204 635 SNEPIPLDAGTLAALnPNRLWVRKLLKGK---AVK---- 666
gi 22654207 640 CGDPMPLGVDLLEQLhPSRMWVRKLRKGK---ALTQKV- 674
gi 22654210 647 FGEPLPLDAKTLAALnPNRFWIRKLLKGR---PVQTRSP 682
gi 20140544 635 SDEPIPMDASTLAALnPNRLWVRKLLKGK---AVKAG-- 668
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