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usp14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) [ Oreochromis niloticus (Nile tilapia) ]

Gene ID: 100691857, updated on 8-Mar-2024

Summary

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Gene symbol
usp14
Gene description
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
See related
Ensembl:ENSONIG00000009436
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis niloticus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Expression
Broad expression in ovary (RPKM 70.4), testis (RPKM 19.9) and 8 other tissues See more
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG18
Exon count:
17
Annotation release Status Assembly LG Location
104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG18 NC_031982.2 (19589404..19598965, complement)
103 previous assembly ASM185804v2 (GCF_001858045.1) LG18 NC_031982.1 (25087830..25097397, complement)

Linkage Group LG18 - NC_031982.2Genomic Context describing neighboring genes Neighboring gene aquaporin-1 Neighboring gene THO complex 1 Neighboring gene Rho-associated, coiled-coil containing protein kinase 1 Neighboring gene GREB1 like retinoic acid receptor coactivator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Oreochromis niloticus Transcriptome or Gene expression
  • Description: Oreochromis niloticus (Nile Tilapia) RNA sequencing from multiple tissues.
  • BioProject: PRJNA78915
  • Analysis date: Fri Dec 29 00:23:36 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables proteasome binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of proteasomal protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 14

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

  1. NC_031982.2 Reference O_niloticus_UMD_NMBU Primary Assembly

    Range
    19589404..19598965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003438082.5 → XP_003438130.1  ubiquitin carboxyl-terminal hydrolase 14 isoform X1

    UniProtKB/TrEMBL
    A0A669AWQ1, A0A669C428
    Related
    ENSONIP00000027796.1, ENSONIT00000059229.1
    Conserved Domains (4) summary
    smart00213
    Location:4 → 74
    UBQ; Ubiquitin homologues
    cd02657
    Location:106 → 480
    Peptidase_C19A; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl ...
    pfam00443
    Location:104 → 479
    UCH; Ubiquitin carboxyl-terminal hydrolase
    cl00155
    Location:5 → 74
    UBQ; Ubiquitin-like proteins

  2. XM_005476446.3 → XP_005476503.1  ubiquitin carboxyl-terminal hydrolase 14 isoform X2

    UniProtKB/TrEMBL
    A0A669C428
    Conserved Domains (3) summary
    cd02657
    Location:80 → 454
    Peptidase_C19A; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl ...
    pfam00443
    Location:78 → 453
    UCH; Ubiquitin carboxyl-terminal hydrolase
    cl00155
    Location:1 → 48
    UBQ; Ubiquitin-like proteins
Nucleotide Protein
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