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OAS2 2'-5'-oligoadenylate synthetase 2 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100659469, updated on 6-Jun-2024

Summary

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Gene symbol
OAS2
Gene description
2'-5'-oligoadenylate synthetase 2
See related
EnsemblRapid:ENSLAFG00000014069
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human all
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Genomic context

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Location:
chromosome: 19
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 19 NC_087360.1 (11086612..11112895)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573490.1 (10599525..10625812, complement)

Chromosome 19 - NC_087360.1Genomic Context describing neighboring genes Neighboring gene 2'-5'-oligoadenylate synthase 1 Neighboring gene 2'-5'-oligoadenylate synthetase 1 Neighboring gene 2'-5'-oligoadenylate synthetase 3 Neighboring gene deltex E3 ubiquitin ligase 1 Neighboring gene RAS protein activator like 1 Neighboring gene cilia and flagella associated protein 73

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2'-5'-oligoadenylate synthetase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of viral genome replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ribonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
2'-5'-oligoadenylate synthase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087360.1 Reference mLoxAfr1.hap2

    Range
    11086612..11112895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003419290.4 → XP_003419338.3  2'-5'-oligoadenylate synthase 2 isoform X1

    UniProtKB/TrEMBL
    G3TCI9
    Related
    ENSLAFP00000021061.2, ENSLAFT00000028297.2
    Conserved Domains (2) summary
    cd05400
    Location:364 → 553
    NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
    pfam10421
    Location:505 → 694
    OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

  2. XM_064272232.1 → XP_064128302.1  2'-5'-oligoadenylate synthase 2 isoform X2

    UniProtKB/TrEMBL
    G3TCI9
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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