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map3k2 mitogen-activated protein kinase kinase kinase 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100493570, updated on 18-Sep-2024

Summary

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Official Symbol
map3k2provided by Xenbase
Official Full Name
mitogen-activated protein kinase kinase kinase 2provided by Xenbase
Primary source
Xenbase:XB-GENE-969986
See related
Ensembl:ENSXETG00000000471
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
17
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (86478834..86499907)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683382.1 (1314362..1335657, complement)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 169 Neighboring gene peroxisomal trans-2-enoyl-CoA reductase Neighboring gene bridging integrator 1 Neighboring gene cytochrome P450 family 27 subfamily C member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    86478834..86499907
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031893159.1 → XP_031749019.1  mitogen-activated protein kinase kinase kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A1B8Y9X0, A0A8J1ITU9
    Conserved Domains (2) summary
    cd06405
    Location:15 → 93
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06652
    Location:328 → 591
    STKc_MEKK2; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 2

  2. XM_002942009.5 → XP_002942055.2  mitogen-activated protein kinase kinase kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A1B8Y9X0, F7ENM6
    Related
    ENSXETP00000118562.1, ENSXETT00000108868.1
    Conserved Domains (2) summary
    cd06405
    Location:51 → 129
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06652
    Location:364 → 627
    STKc_MEKK2; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 2
Nucleotide Protein Strain
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