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APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 [ Ailuropoda melanoleuca (giant panda) ]

Gene ID: 100482041, updated on 8-Mar-2024

Summary

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Gene symbol
APEX1
Gene description
apurinic/apyrimidinic endodeoxyribonuclease 1
Locus tag
PANDA_019762
See related
Ensembl:ENSAMEG00000005418
Gene type
protein coding
RefSeq status
MODEL
Organism
Ailuropoda melanoleuca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
7
Annotation release Status Assembly Chr Location
103 current ASM200744v2 (GCF_002007445.1) 20 NC_048237.1 (579654..582814)
102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003219164.1 (159001..161989, complement)

Chromosome 20 - NC_048237.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 33 Neighboring gene uncharacterized LOC117797234 Neighboring gene O-sialoglycoprotein endopeptidase Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 Neighboring gene U12 minor spliceosomal RNA Neighboring gene purine nucleoside phosphorylase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sequence and de novo assembly of the giant panda genome. Li R, et al. Nature, 2010 Jan 21. PMID 20010809, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA 3'-5' DNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA-(apurinic or apyrimidinic site) lyase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM200744v2 Primary Assembly

Genomic

  1. NC_048237.1 Reference ASM200744v2 Primary Assembly

    Range
    579654..582814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002929511.4 → XP_002929557.1  DNA-(apurinic or apyrimidinic site) lyase

    See identical proteins and their annotated locations for XP_002929557.1

    UniProtKB/TrEMBL
    D2I2U8
    Related
    ENSAMEP00000005721.1, ENSAMET00000005961.2
    Conserved Domains (1) summary
    cd09087
    Location:62 → 316
    Ape1-like_AP-endo; Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases

  2. XM_002929510.4 → XP_002929556.1  DNA-(apurinic or apyrimidinic site) lyase

    See identical proteins and their annotated locations for XP_002929556.1

    UniProtKB/TrEMBL
    D2I2U8
    Conserved Domains (1) summary
    cd09087
    Location:62 → 316
    Ape1-like_AP-endo; Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases

  3. XM_019810210.2 → XP_019665769.1  DNA-(apurinic or apyrimidinic site) lyase

    UniProtKB/TrEMBL
    D2I2U8

  4. XM_011237557.3 → XP_011235859.1  DNA-(apurinic or apyrimidinic site) lyase

    See identical proteins and their annotated locations for XP_011235859.1

    UniProtKB/TrEMBL
    D2I2U8
    Conserved Domains (1) summary
    cd09087
    Location:62 → 316
    Ape1-like_AP-endo; Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases

  5. XM_034648425.1 → XP_034504316.1  DNA-(apurinic or apyrimidinic site) lyase

    UniProtKB/TrEMBL
    D2I2U8
Nucleotide Protein
Heading Accession and Version

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