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WDR45 WD repeat domain 45 [ Sus scrofa (pig) ]

Gene ID: 100462757, updated on 17-Aug-2024

Summary

Official Symbol
WDR45provided by VGNC
Official Full Name
WD repeat domain 45provided by VGNC
Primary source
VGNC:VGNC:94922
See related
Ensembl:ENSSSCG00000012290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in heart (RPKM 52.8), psoas major muscle (RPKM 35.9) and 8 other tissues See more
Orthologs
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Genomic context

See WDR45 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) X NC_010461.5 (43150691..43155981, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) X NC_010461.4 (47998631..48003934, complement)

Chromosome X - NC_010461.5Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 120 Neighboring gene PRA1 domain family member 2 Neighboring gene G-patch domain and KOW motifs Neighboring gene MAGI family member, X-linked

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-3,5-bisphosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphatidylinositol-3-phosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagy of mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in nucleophagy IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein lipidation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein localization to phagophore assembly site IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extrinsic component of membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in phagophore assembly site membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
WD repeat domain phosphoinositide-interacting protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190293.1NP_001177222.1  WD repeat domain phosphoinositide-interacting protein 4

    See identical proteins and their annotated locations for NP_001177222.1

    Status: PROVISIONAL

    Source sequence(s)
    HM046518
    UniProtKB/TrEMBL
    A0A8D0LSF5, A0A8D1H503, D7RA32, F1RW55
    Related
    ENSSSCP00000013078.4, ENSSSCT00000013438.6
    Conserved Domains (2) summary
    sd00039
    Location:196232
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:187274
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010461.5 Reference Sscrofa11.1 Primary Assembly

    Range
    43150691..43155981 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013986108.2XP_013841562.1  WD repeat domain phosphoinositide-interacting protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8D0LSF5
    Conserved Domains (3) summary
    COG2319
    Location:137288
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:214250
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:205292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_013986111.2XP_013841565.1  WD repeat domain phosphoinositide-interacting protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8D0LSF5, A0A8D1H503, D7RA32, F1RW55
    Conserved Domains (2) summary
    sd00039
    Location:196232
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:187274
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_013986110.2XP_013841564.1  WD repeat domain phosphoinositide-interacting protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8D0LSF5
    Conserved Domains (3) summary
    COG2319
    Location:137288
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:214250
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:205292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. XM_013986109.2XP_013841563.1  WD repeat domain phosphoinositide-interacting protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8D0LSF5
    Conserved Domains (3) summary
    COG2319
    Location:137288
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:214250
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:205292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...