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PLCD1 phospholipase C delta 1 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100462440, updated on 26-Mar-2024

Summary

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Gene symbol
PLCD1
Gene description
phospholipase C delta 1
Locus tag
CR201_G0006430
See related
Ensembl:ENSPPYG00000014014
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 2 NC_085928.1 (116481110..116503396)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 3 NC_071988.1 (104300524..104322742)

Chromosome 2 - NC_085928.1Genomic Context describing neighboring genes Neighboring gene MYD88 innate immune signal transduction adaptor Neighboring gene acetyl-CoA acyltransferase 1 Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene villin like Neighboring gene CTD small phosphatase like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_085928.1 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    116481110..116503396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003776286.5 → XP_003776334.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8WYE8, A0A6D2W9H1, H2PB61
    Related
    ENSPPYP00000015676.2
    Conserved Domains (4) summary
    cd00275
    Location:629 → 755
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:295 → 596
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:22 → 139
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:144 → 283
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

  2. XM_054552323.2 → XP_054408298.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X3

  3. XM_002813936.6 → XP_002813982.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8WYB6, A0A8I5TPK8
    Related
    ENSPPYP00000032790.1
    Conserved Domains (4) summary
    cd00275
    Location:650 → 776
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:316 → 617
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:43 → 160
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:165 → 304
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)
Nucleotide Protein
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